Results 191 to 200 of about 31,723,296 (295)

Improving peripheral arterial catheter placement in critically ill children: a pre-post quality improvement study. [PDF]

Front Pediatr
Zhou M, Fu K, Li J, Wang Q, Yang N, Zeng L, Wang L.   +6 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Constructing pathways for glycine betaine in cross-domain ecological restoration: a bibliometric analysis. [PDF]

PeerJ
Wu Z, Li J, Ma Z, Zhou J, Huang H.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Simultaneous Determination of Three Residual Monomers in Polyvinyl Alcohol Eye Drops Using a Dual-Wavelength RP-HPLC Method and Evaluation of Its Greenness. [PDF]

Biomed Chromatogr
Zeyan Y, Wenfen G, Zhiyuan L, Xiaobin M, Yongfei L.   +4 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Motor Improvements Following Non-Invasive Brain Stimulation with kTMP: A Case Study of Cerebellar Stroke. [PDF]

Cerebellum
Chirino-Pérez A, Merrick CM, Miranda-Casasola F, Labruna L, Sheltraw D, Ivry RB.   +5 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

In vivo quantification of knee-orthosis valgus-corrective moment during gait: Effects of medial strut length on external knee adduction moment in medial knee osteoarthritis. [PDF]

PLoS One
Nakano K, Mine Y, Katsuhira J, Yamauchi K, Kitashiro M, Nomoto S.   +5 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source