Results 241 to 250 of about 32,792,145 (340)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Tobacco retail characteristics across urban and rural districts in Lao PDR: an observational study, 2024. [PDF]

Front Public Health
Kulkarni S, Bui TC, Xangsayarath P, Phangdouangsy K, Soulaphy C, Sengdara K, Martinez SA, Janitz A, Frank-Pearce SG, Beebe LA.   +9 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Pore Evolution Mechanisms in the Longmaxi Formation Shale Reservoir of the Anchang Syncline under Basin-Mountain Tectonic Evolution. [PDF]

ACS Omega
Zhao Y, Wang Y, Zhang H, Chen S, Chen H, Wang H, Zhang J.   +6 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Time-dependent diffusion MRI differentiates atypical from conventional uterine leiomyomas: A preliminary study. [PDF]

Eur J Radiol Open
Yu J, Du Z, Wang Y, Teng M, Li W, Tang R, Wu D, Cheng J, Fu L.   +8 more
europepmc   +1 more source

Association mapping of wheat distinctness, uniformity, and stability traits identifies evidence of <i>TaDof-B</i> copy number variation associated with stem pith thickness. [PDF]

Front Plant Sci
Love B, Bansept-Basler P, Barber T, Bedford JA, Berry S, Bird N, Borum F, Brown J, Bryant R, Chia T, Connell J, Fenwick P, Feuerhelm D, Flatman E, Gosman N, Hayes C, Henriksson T, Jack P, Kerton M, Lage J, McMillan V, Nielsen LK, Percival-Alwyn L, Schondelmaier J, Sharma R, Smith S, Tailby P, Vallenback P, Wallace M, Warner D, Wright TIC, Yang CJ, Zanella CM, Gardner KA, Mackay IJ, O'Sullivan DM, Cockram J.   +36 more
europepmc   +1 more source

Can conceptual beliefs shape impressions from voices? [PDF]

Psychon Bull Rev
Irvine M, Lavan N.
europepmc   +1 more source