Three-component radical homo Mannich reaction [PDF]
Due to the ionic nature of its mechanism, the Mannich reaction can only use non-enolizable aldehydes as substrates. Here, the authors expand the scope of the classical Mannich reaction to enolizable aldehydes by employing a radical process resulting in a
Shuai Shi +5 more
doaj +3 more sources
Catalytic Three‐Component Ugi Reaction [PDF]
Perfect atom economy characterizes a novel catalytic three‐component Ugi reaction (see example). Different α‐amino amides are formed in good yields from aldehydes, primary amines, and isocyanides in the presence of phenyl phosphinic acid as the catalyst. The products will be useful for the synthesis of α‐amino acid derivatives and in diversity‐oriented
Pan, S., List, B.
openaire +3 more sources
DFT Studies on the Stereoselective Three-Component Ugi Reaction
Mechanism and stereochemistry of three component Ugi reaction (3C-Ugi) were studied theoretically based on DFT calculations. Structures of reagents, products, intermediates, and transition states were optimized at M062X/6-31+g(d,p) level of theory in gas
Elaheh Sadat Sharifzadeh +1 more
doaj +3 more sources
Isoxazole is a five membered heterocyclic compound which is an azole with an oxygen atom next to nitrogen. The substituted isoxazole derivatives show various biological activities like antimicrobial, antiviral, anti-inflammatory, antioxidant, anticancer ...
Parul Setia, Ruchi Bharti, Renu Sharma
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Stabilization of gold nanoparticles on copper ferrrite and its application as bimetallic and magnetically recyclable catalyst for preparation of propargylamines [PDF]
In this report for the first time, gold nanoparticles were supported and stabilized on copper ferrite nanoparticles (CuFe2O4 NPs) and obtained compound was characterized by different techniques such as transmission electron microscopy (TEM), X-ray ...
Mohammad Gholinejad +3 more
doaj +1 more source
Novel pH-sensitive catechol dyes synthesised by a three component one-pot reaction
The synthesis and characterisation of new dyes based on indolizines bearing catechol groups in their structure is presented. The preparation was carried out through a simple three component one-pot reaction promoted by CuNPs/C, between pyridine-2 ...
Juan José Calmels +7 more
doaj +1 more source
Photoinduced Synthesis of Sulfonyl-Containing Phosphorothioates via a Three-Component Reaction
Both sulfonyl and phosphorothioate are important privileged structural motifs which are widely presented in pharmaceuticals and agrochemicals. Herein, we describe an efficient approach to synthesizing sulfonyl-containing phosphorothioates by merging ...
Xianda Wu +5 more
doaj +1 more source
Sufficient conditions for wave instability in three-component reaction-diffusion systems [PDF]
Sufficient conditions for the wave instability in general three-component reaction-diffusion systems are derived. These conditions are expressed in terms of the Jacobian matrix of the uniform steady state of the system, and enable us to determine whether
Hata, Shigefumi +2 more
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Alkoxyallene‐Based LANCA Three‐Component Synthesis of 1,2‐Diketones, Quinoxalines, and Unique Isoindenone Dimers and a Computational Study of the Isoindenone Dimerization [PDF]
A series of β‐alkoxy‐β‐ketoenamides was prepared by the well‐established LANCA three‐component reaction of lithiated 1‐(2‐trimethylsilylethoxy)‐substituted allenes, nitriles, and α,β‐unsaturated carboxylic acids.
Bera M. K. +6 more
core +1 more source
The present study deals with the synthesis, spectroscopic characterization, antibacterial and antifungal activities of novel series five-membered ring heterocyclic compounds containing nitrogen and sulfur heteroatoms.
Trifa Khalaf Mohammed +2 more
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