Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Determination of Hydroquinone Clathrate Stability for Different Guest Molecules Using <i>NPH</i> Ensemble Molecular Dynamics. [PDF]
Energy FuelsGarcía BR +5 more
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Phase Equilibria and Morphology of the TPU-Tactix-DGEBA Ternary System: Interference Approach and SEM Analysis. [PDF]
Polymers (Basel)Ponomarenko AD +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Metal-Spinel-Corundum Three Phase Equilibria in the System Ni-Cr-Al-O at 1373 Κ
High Temperature Materials and Processes, 2007 Jacob, K.T. +2 more
doaj +1 more source
Implementation of artificial intelligence in healthcare: a protocol for a phased mixed-methods multiple case study in the North Denmark Region. [PDF]
BMJ OpenHald K +4 more
europepmc +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Gender Equity and Decent Work in the Health Workforce in Nepal: Insights From Community Health Volunteers, Nurses, and Doctors. [PDF]
Nurs Health SciBigler C, K C S, Thieme S.
europepmc +1 more source