Results 131 to 140 of about 33,716,273 (299)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Are environmental factors for atopic eczema in ISAAC phase three due to reverse causation?

, 2019
: Some previously described environmental associations for atopic eczema may be due to reverse causation. We explored the role of reverse causation by comparing individual-and school-level results for multiple atopic eczema risk factors.
Cepeda, A. M., Barba, S., Riikjarv, M-A, Bhave, S., Beasley, R., Gomez, M., Onadeko, B. O., Rennie, D., Del-Rio-Navarro, B. E., Flohr, C., Setty, G., Romieu, I, Amarales, L., al-Momen, J. A., MacKay, R., Konthen, P., de Freitas Souza, L., Joshi, M. K., Sukumaran, T., Howitt, M. E., Imanalieva, C., Ramirez-Chanona, N., Koffi, B. N., Merida-Palacio, J., V, Singh, V, Shah, J., Standring, P., Bjorksten, B., Asher, M., I, Ellwood, Philippa, Bustos, C., Barragan-Meijueiro, M., Asher, Innes, Suprihati, W., Ordonez, G. A., Jain, K. C., Rego, S., Lee, B. W., Cua-Lim, F., Ellwood, E., Pattemore, P., Lai, C. K., Chiarella, P., Bouayad, Z., Pearce, Neil, Tuuau-Potoi, N., Cukier, G., Khatav, V. A., Silverwood, Richard J., Awasthi, S., Rutter, Charlotte E., Aguirre, V, Robertson, C. F., Sabir, M., Weiland, S. K., Strachan, D., Foliaki, S., Pherwani, A., V, Kartasasmita, C. B., Langan, Sinead M., Keil, U., Weyler, Joost J., Mantri, S. N., Clayton, T. O., Sa'aga-Banuve, R., Sears, M., Linares-Zapien, F. J., Odhiambo, J., Brunekreef, B., Aguilar, P., Sole, D., Benavides, L. A., von Mutius, E., da Cunha, A. J., Hanumante, N. M., Kunii, O., Strachan, David P., Zsigmond, G., Williams, Hywel C., Kudzyte, J., Garcia-Almaraz, R., Wong, G., Gonzalez-Diaz, S. N., Pearce, N., Baena-Cagnani, C. E., Contreras, A., Nishima, S., Pekkanen, J., Garcia-Marcos, Luis, Garcia-Marcos, L., Hypolite, I. E., Chen, Y-Z, Ait-Khaled, N., Anderson, R., Forastiere, F., Aristizabal, G., Anderson, H. R., de Bruyne, J., Mallol, J., Novak, Z., Odajima, H., Baeza-Bacab, M., Kuaban, C., Ferguson, A., Crane, J., Williams, H. C., Lai, C. K. W., Quah, B. S., Montefort, S., Sharma, S. K., Pinto-Vargas, R., Pan, Q. Li, Masjedi, M. R., Melaku, K., Babu, P. S. Suresh, Moyes, C., Weinmayr, G., Romero-Tapia, S., Zhong, N. S., Teh, K. H., Breborowicz, A., Baratawidjaja, K., El Sony, A., Ellwood, P., Salvi, S., Steriu, A., Stewart, A. W., Mitchell, E. A.   +127 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Three-Dimensional System-in-Package Using Stacked Silicon Platform Technology

, 2005
In this paper, a novel method of fabricating three– dimensional (3-D) system-in-package (SiP) using a silicon carrier that can integrate known good dice with an integrated cooling solution is presented.
Rotaru, Mihai D, Iyer, Mahadevan, Kripesh, Vaidyanathan, Yoon, Seung Wook, Ganesh, V. P., Khan, Navas, Fang, Wang   +6 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Gold Nanoparticle Monolayers from Sequential Interfacial Ligand Exchange and Migration in a Three-Phase System. [PDF]

Sci Rep, 2016
Yang G, Hallinan DT.
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source