Results 141 to 150 of about 18,606 (197)

CD28 and CTLA4 polymorphisms associated with ankylosing spondylitis: a study in the context of HLA-B27. [PDF]

BMC Immunol
Yu KH, Wu GH, Yang CJ, Lin WT, Hsu FP, Chen DP.   +5 more
europepmc   +1 more source

Advancements in genetic analysis: Insights from a case study and review of next‐generation sequencing techniques for veterinary oncology applications

Veterinary Clinical Pathology, EarlyView.
Abstract Acute myeloid leukemia (AML) poses significant challenges in veterinary medicine, with limited treatment options and poor survival rates. While substantial progress has been made in characterizing human AML, translating these advancements to veterinary practice has been hindered by limited molecular understanding and diagnostic tools. The case
R. Adam Harris, Jillian Nolan, Dylan Ammons, Samantha Beeson, Douglas Thamm, Anne Avery   +5 more
wiley   +1 more source

Comparative Genomics and Phylogenetic Analyses of <i>Aquarius macrophyllus</i> and Related Genera in Alismataceae Based on Plastome Data. [PDF]

Ecol Evol
Li J, Wei S, Ying J, Lu Q.
europepmc   +1 more source

Optimised Ribosome Profiling Reveals New Insights Into Translational Regulation in Synchronised Chlamydomonas reinhardtii Cultures

Plant, Cell &Environment, Volume 48, Issue 9, Page 6982-7000, September 2025.
ABSTRACT Deep sequencing of ribosome footprints, also known as ribosome profiling (Ribo‐seq), enables the quantification of mRNA translation and a comprehensive view of the translatome landscape. Here, we report an optimised Ribo‐seq protocol and analysis pipeline for the model green alga, Chlamydomonas reinhardtiii (Chlamydomonas).
Yen‐Ling Lin, Eva Yuhua Kuo, Shih‐Yi Wang, Chih‐Chi Lee, Su‐Chiung Fang   +4 more
wiley   +1 more source

Heterologous prime-boost vaccination drives stromal activation and adaptive immunity against SARS-CoV-2 variants. [PDF]

Front Immunol
Jeon JH, Kim S, Kim SY, Shin KS, Park B, Chang S, Kang CY, Kim YJ, Park JE, Youk S, Kim D, Yeo J.   +11 more
europepmc   +1 more source

Targeting the mTOR Signaling Pathway Through miR‐100 and miR‐101 in De Novo Acute Myeloid Leukemia: Implications for Therapeutic Intervention

Cancer Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background Microribonucleic acid (MicroRNAs/miRNAs) play a significant role in cancer progression by changing cellular functions through the modulation of protein expressions. The potential of different miRNAs to alter the expression of the mammalian target of rapamycin (mTOR)/protein kinase B (PKB or AKT)/phosphatidylinositol‐3‐kinase (PI3K ...
Maryam Kargar, Mehdi Allahbakhshian Farsani, Javad Garavand, Mahnaz Gorji, Mohammad Rafiee, Seyed Sobhan Bahreiny, Mohammad Hossein Mohammadi   +6 more
wiley   +1 more source

Optimizing 5'UTRs for mRNA-delivered gene editing using deep learning. [PDF]

Nat Commun
Castillo-Hair S, Fedak S, Wang B, Linder J, Havens K, Certo M, Seelig G.   +6 more
europepmc   +1 more source

Efficient creation of decorative double‐flowered petunia through CRISPR/Cas9‐mediated simultaneous editing of PMADS3 and FBP6 genes

Plant Biotechnology Journal, EarlyView.
Yingshuang Xue, Chong Wang, Rong Ge, Shuang Lu, Jing Ni, Yusheng Duan, Zheng Hong, Hui Zhang   +7 more
wiley   +1 more source

The Role of PIWI‐Interacting RNA in Urologic Carcinoma and Its Clinical Implications

Cancer Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Piwi‐interacting RNA (piRNA) represents a class of small non‐coding RNA molecules, typically ranging in length from 18 to 35 nucleotides. These molecules are critically involved in the preservation of genomic integrity and the regulation of protein translation processes.
Jiajia Cai, Shirui Jiang, Dongdong Lu, Ghulam Murtaza, Mingbang Wang, Yuqing Li, Da Shi, Yingrui Li, Hu Fang, Song Wu   +9 more
wiley   +1 more source

Genome-Wide Association Study Identifying a Novel Gene Related to a History of Febrile Convulsions in Patients With Focal Epilepsy. [PDF]

J Clin Neurol
Kim J, Lee HJ, Park HJ, Lee JH, Kim WJ.
europepmc   +1 more source