Immunoinformatic-driven design and evaluation of multi-epitope mRNA vaccine targeting HIV-1 gp120. [PDF]
Ahmed MZ+5 more
europepmc +1 more source
Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina+8 more
wiley +1 more source
Alternative 3' UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD. [PDF]
Eck RJ+3 more
europepmc +1 more source
Pra‐GE‐ATLAS: Empowering Pinus radiata stress and breeding research through a multi‐omics database
Gymnosperms represent molecular and ecological diversity hotspots, yet they remain understudied due to limited community resources. To address this gap, the P(inus)ra(diata)‐G(ene)E(xpression)‐ATLAS provides a refined multi‐omics platform for Pinus radiata that advances conifer research and facilitates the evaluation of conserved plant molecular ...
Víctor Roces+3 more
wiley +1 more source
Conditional knockdown of gene expression in plants via 3' UTR editing. [PDF]
Liu T+9 more
europepmc +1 more source
Genetic adaptation despite high gene flow in a range‐expanding population
Abstract Signals of natural selection can be quickly eroded in high gene flow systems, curtailing efforts to understand how and when genetic adaptation occurs in the ocean. This long‐standing, unresolved topic in ecology and evolution has renewed importance because changing environmental conditions are driving range expansions that may necessitate ...
Andy Lee+9 more
wiley +1 more source
Viral Metagenomics of the Bharal (<i>Pseudois nayaur</i>) within the Qinghai-Tibet Plateau Revealed Diverse Viruses. [PDF]
Zhang E+10 more
europepmc +1 more source
Genetic Architecture of Immune Cell DNA Methylation in the Rhesus Macaque
ABSTRACT Genetic variation that impacts gene regulation, rather than protein function, can have strong effects on trait variation both within and between species. Epigenetic mechanisms, such as DNA methylation, are often an important intermediate link between genotype and phenotype, yet genetic effects on DNA methylation remain understudied in natural ...
Christina E. Costa+12 more
wiley +1 more source
Effects of Naphtho[2,1-a]pyrene Exposure on CYP1A1 Expression: An in Vivo and in Vitro Mechanistic Study Exploring the Role of m6A Posttranscriptional Modification. [PDF]
Shen J+15 more
europepmc +1 more source
miR-365 promotes HOXA9-mediated differentiation of mesenchymal stem cells to nucleus pulposus cells by interacting with HIF-1α. [PDF]
Zhi ZZ+5 more
europepmc +1 more source