Results 21 to 30 of about 34,778 (266)
Genistein-induced mir-23b expression inhibits the growth of breast cancer cells [PDF]
, 2015 Aim of the study: Genistein, an isoflavonoid, plays roles in the inhibition of protein tyrosine kinase phosphorylation, induction of apoptosis, and cell differentiation in breast cancer.
Avci, C.B. +6 more
core +2 more sources
Cloning, Expression, Sequence Analysis and Homology Modeling of the Prolyl Endoprotease from Eurygaster integriceps Puton [PDF]
, 2014 Eurygaster integriceps Puton, commonly known as sunn pest, is a major pest of wheat in Northern Africa, the Middle East and Eastern Europe. This insect injects a prolyl endoprotease into the wheat, destroying the gluten.
Clack, Beatrice A. +5 more
core +3 more sources
The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes [PDF]
, 2019 Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs.
Bertzbach, Luca D. +7 more
core +2 more sources
Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. [PDF]
, 2016 The unintended consequences of gene targeting in mouse models have not been thoroughly studied and a more systematic analysis is needed to understand the frequency and characteristics of off-target effects.
Adkisson, Michael +9 more
core +4 more sources
International Journal of General Medicine, 2021 Objective Alternative polyadenylation (APA) is a common mechanism that is present in most human genes and determines the length of the messenger ribonucleic acid (mRNA) three prime untranslated region (3ʹ-UTR), which can give rise to changes in mRNA ...
Jian Li, Wen Chen, Yi Cao, Zhengrong Li
semanticscholar +1 more source
Scientific Reports, 2017 To explore novel molecular mechanisms underlying obesity, we applied a systems genetics framework to integrate risk genetic loci from the largest body mass index (BMI) genome-wide association studies (GWAS) meta-analysis with mRNA and microRNA profiling ...
Hao He +11 more
doaj +1 more source
Human Cytomegalovirus Encoded miR-US25-1-5p Attenuates CD147/EMMPRIN-Mediated Early Antiviral Response. [PDF]
, 2017 Cellular receptor-mediated signaling pathways play critical roles during the initial immune response to Human Cytomegalovirus (HCMV) infection.
Chen, Huizi +6 more
core +5 more sources
Viruses, 2017 Influenza A virus (IAV) infection remains a significant cause of morbidity and mortality worldwide. One key transcription factor that is activated upon IAV infection is nuclear factor Kappa B (NF-κB).
Sreekumar Othumpangat +3 more
doaj +1 more source
Diabetes, 2014 Long-term glucocorticoid (GC) treatment induces central fat accumulation and metabolic dysfunction. We demonstrate that microRNA-27b (miR-27b) plays a central role in the pathogenesis of GC-induced central fat accumulation.
Xiaocen Kong +15 more
semanticscholar +1 more source
Journal of Immunology Research, 2018 Although aberrant expression of miR-34a, an essential tumor suppressor miRNA, has been frequently observed in colon cancer (CCa), whether miR-34a can regulate CCa progression by modulating other facets of this malignancy (such as multidrug resistance ...
Yong Li +8 more
doaj +1 more source