Results 41 to 50 of about 34,778 (266)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
International Journal of General Medicine, 2021 Jian Li,1 Wen Chen,2 Yi Cao,3 Zheng-Rong Li3 1Department of Gastrointestinal Surgery, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, 330000, People’s Republic of China; 2Key Laboratory of Bioprocess Engineering of ...
Li J, Chen W, Cao Y, Li ZR
doaj
Cloning of the Complete Gene for Carcinoembryonic Antigen [PDF]
, 1990 Carcinoembryonic antigen (CEA) is a widely used tumor marker, especially in the surveillance of colonic cancer patients. Although CEA is also present in some normal tissues, it is apparently expressed at higher levels in tumorous tissues than in ...
Bona, Marion +8 more
core
Alzheimer's disease and HIV associated dementia related genes: I. location and function. [PDF]
, 2008 Alzheimer's disease (AD), the most common cause of dementia, has few clinical similarities to HIV-1-associated dementia (HAD). However, genes were identified related among these dementias.
Chiappelli, Francesco +5 more
core +3 more sources
Conformational dynamics of the hepatitis C virus 3′X RNA
RNA: A publication of the RNA SocietyThe 3′ end of the hepatitis C virus genome is terminated by a highly conserved, 98 nt sequence called 3′X. This untranslated structural element is thought to regulate several essential RNA-dependent processes associated with infection.
Parker D Sperstad, Erik D. Holmstrom
semanticscholar +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Cloning and characterisation of the rad9 DNA repair gene from Schizosaccharomyces pombe [PDF]
, 1991 The rad9.192 DNA repair mutant from the fission yeast, Schizosaccharomyces pombe, is sensitive to both UV and ionising radiation. The rad9 gene has been cloned by complementation of the gamma-ray sensitivity of the mutant cell line.
Carr, Antony M +3 more
core +2 more sources
Biomedicines, 2018 Lymphedema is a condition resulting from mutations in various genes essential for lymphatic development and function, which leads to obstruction of the lymphatic system.
M. Hadizadeh +10 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source