Results 161 to 170 of about 3,059 (280)

The Three Seas Initiative as a concept of security and economic development of Eastern Europe

, 2018
Artykuł dotyczy Inicjatywy Państw Trójmorza (IPT), zaproponowanej przez Polskę i Chorwację w sierpniu 2016 r. na i Szczycie IPT w Dubrowniku. Autor skupił się na rezultatach II Szczytu Inicjatywy, który odbył się 6-7 lipca 2017 r. w Warszawie. Wyjaśniono
Baziur, Grzegorz
core  

Stress and resilience in northern European marine ecosystems. [PDF]

Proc Natl Acad Sci U S A
Llope M, Blenckner T, Vasilakopoulos P, McGinty N, Lynam CP, Hélaouët P, Möllmann C, Frelat R, Durant JM, Stige LC, Stenseth NC.   +10 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Survey Dataset Supporting Blue Circular Economy Strategies for Bivalve Shell Waste Valorisation. [PDF]

Data Brief
Bellei P, Magalhães FC, Mendes MP, Silva RV, Pereira MFC, Dias APS, Jenssen M, Solstad RG, Kioumarsi M, Flores-Colen I.   +9 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The Global Deep Sea Exploration Goals: A representative approach to visually observing the deep seafloor. [PDF]

Sci Adv
Johannes KN, Poulton SE, Kennedy BRC, Bell KLC.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Leveraging port state measures to combat illegal, unreported, and unregulated fishing. [PDF]

Sci Adv
Selig ER, Wabnitz CCC, Nakayama S, Park J, Barnes R, Blasiak R, Borg-Costanzi D, Golder B, Jouffray JB, Leape J, Decker Sparks JL.   +10 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Logistics chains and exports among the member countries of the Three Seas Initiative

Diplomski rad analizira logističke lance i izvozni potencijal među zemljama članicama Inicijative triju mora s posebnim naglaskom na trgovinske tokove, prometnu infrastrukturu i logističke kapacitete unutar regije.
Šimunović, Karla
core   +2 more sources