Results 191 to 200 of about 12,161,773 (274)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Prioritizing Shark, Ray, and Chimaera Conservation in Rapidly Changing Polar Waters. [PDF]

Glob Chang Biol
Bettcher VB, Batlle-Morera A, Kyne PM, Charles R, García-Rodríguez E, Rohner CA, Armstrong AO, O'Leary Amsler M, Chernova NV, Devine BM, Dolgov AV, Donovan MM, Faure J, Finucci B, Fisher JAD, Forbes RAS, Hedges KJ, Hollyman PR, Hussey NE, Jac R, Kulka DW, Orlov AM, Péron C, Schaber M, Ste-Marie E, Weigmann S, Jabado RW.   +26 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

The Antarctic coastal ocean heat budget is dominated by heat loss to land ice melt. [PDF]

Sci Adv
Moorman R, Thompson AF, Youngs MK, Stewart AL.   +3 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

THREE SEAS INITIATIVE: PROSPECTS AND CHALLENGES FOR UKRAINE

Visnyk of the Lviv University
openaire   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Ten-valley excitonic complexes in charge-tunable monolayer WSe₂. [PDF]

Nat Commun
Dijkstra A, Ben Mhenni A, Van Tuan D, Çetiner E, Schur-Wilkens M, Kim J, Steiner L, Watanabe K, Taniguchi T, Barbone M, Wilson NP, Dery H, Finley JJ.   +12 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Particle-associated diazotrophs drive nitrogen fixation in Arctic subsurface waters of the Barents Sea. [PDF]

Nat Commun
Benavides M, Coët A, Sebastián M, Vogts A, Furbo Reeder C, Cerdán-García E, Norman L, Hawley R, Flanagan O, Lohan MC, Hopkins JE, Mahaffey C.   +11 more
europepmc   +1 more source