Results 41 to 50 of about 11,447,501 (301)
Cost-effectiveness thresholds or decision-making threshold: a novel perspective
Cost Effectiveness and Resource Allocation, 2023 AbstractThe use of multiple cost-effectiveness thresholds in pharmacoeconomic evaluation is a hotly debated topic in the international academic community. This study analyzed and discussed thresholds in the context of pharmacoeconomic evaluation and reimbursement decision-making.
Lihua Sun +3 more
openaire +3 more sources
Effect of ESS on Olfactory Threshold of Patients with CRS without Nasal Polyps. [PDF]
, 2018 peer reviewedOBJECTIVES: Chronic rhinosinusitis (CRS) is characterized by a long-time inflammatory disease of nasal and sinus mucosa. Olfactory dysfunction is common among CRS patients with a prevalence ranging from 48% to 83%.
Bagherihagh, Ali +7 more
core +1 more source
A Bayesian nonlinearity test for threshold moving average models [PDF]
, 2010 We propose a Bayesian test for nonlinearity of threshold moving average (TMA) models. First, we obtain the marginal posterior densities of all parameters, including the threshold and delay, of the TMA model using Gibbs sampler with the Metropolis ...
Liu, Jinshan +3 more
core +4 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Coordination under threshold uncertainty in a public goods game [PDF]
We explored experimentally how threshold uncertainty affects coordination success in a threshold public goods game. Whereas all groups succeeded in providing the public good when the exact value of the threshold was known, uncertainty was generally ...
Reif, Christiane +4 more
core +2 more sources
InsectsPine wilt disease (PWD) is an economically important disease. With the increasing temperature caused by climate change, there is a concern that it may expand to regions currently at low risk, cause more serious ecological harm and economic losses in ...
Ruicong Zhang +6 more
doaj +1 more source
The Financial Sustainability of State-Owned Enterprises in an Emerging Economy
Economies, 2022 When the government creates state-owned enterprises (SOEs), one of the primary purposes is to reduce its financial burden in the long run, also called financial sustainability.
Chee Loong Lee +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Frontiers in Public HealthIntroductionIn the context of China’s new urbanization strategy and its “dual-carbon” goals, understanding the impact of urban transformation on carbon emissions in the residential sector is crucial.
Yongkun Wang, Zhuo Tong, Yunhui Zhang
doaj +1 more source