The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Attacks on Threshold Signature Schemes with Traceable Signers
, 2012 [[abstract]]In 1998, Wang et al. proposed two new (t,n)-threshold signature schemes with traceable signers that can withstand conspiracy attacks without attaching a secret number.
Tseng, Yuh-Min; Jan, J. K.
core
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
An Efficient Group-oriented (t,n) Threshold Signature Scheme with Message Linkage [PDF]
, 2012 [[abstract]]In 1999, Chen (1999) proposed several signature schemes in his graduate thesis. One is a group-oriented (t,n) threshold signature scheme in which the (t,n) threshold signature is based on an RSA scheme.
Perng, Chi-Yow; Jan, Jinn-Ke; Tseng, Yuh-Min
core
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
On the Efficiency of Nonrepudiable Threshold Proxy Signature Scheme with Known Signers
, 2012 [[abstract]]In the (t,n) proxy signature scheme, the signature signed by the original signer can be signed by t or more proxy signers out of a proxy group of n proxy signers. Recently, Hsu et al.
黃明祥;Hwang, Min-Shiang
core
Security of Wang et al.'s group-oriented (t,n) threshold signature schemes with traceable signers
, 2001 A forgery attack on the group-oriented (t,n) threshold signature schemes was described. The scheme consists of three phases namely the initiation, the individual signature generation and verification phase, and the group signature generation and ...
H.W. Chan +11 more
core +1 more source
Faster threshold-SM2 with identifiable abort and non-interactive online signing
CybersecurityThreshold signatures are essential for fault-tolerant applications among groups of users, such as in blockchain transactions. SM2 is a digital signature standard in China and ISO, yet its threshold variant is less developed compared to international ...
Yunlv Lv +3 more
doaj +1 more source
Preoperative staging CT-based radiomics signature in predicting Ki-67 status in breast cancer
肿瘤影像学, 2020 Objective: To explore the additional value of preoperative CT-based radiomics signature for non-invasive prediction of Ki-67 proliferation index in breast cancer.
LI Jiao +7 more
doaj
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source