Results 91 to 100 of about 5,278,573 (290)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Higher-Order Threshold Implementation of the AES S-Box [PDF]
, 2016 H2020 644052 ...
De Cnudde, Thomas +4 more
openaire +4 more sources
Threshold concept knowledge in analogue electronics: Support and assessment [PDF]
, 2012 In electrical engineering, as in other academic disciplines, there exist special, threshold concepts, where students often get stuck but which once grasped reveal new ways of thinking about a subject.
Scott, Jonathan B. +2 more
core
FEBS Open Bio, EarlyView.Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley +1 more source
Comparative Power-Delay Performance Analysis of Threshold Logic Technologies
, 2015 Recent focus in energy efficiency is motivated with diminishing conventional energy resources, and increasing demand in low power applications with shrinking platform sizes.
Ercan, Furkan, Muhtaroglu, Ali
core
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Strategy for soil and water management in the Thames River Basin [PDF]
, 1982 This report presents a summary of the Thames River Implementation Committee program and discusses the key program recommendations related to policy, community education, land use management and conservation practices.Ontario Ministry of the ...
Thames River Implementation Committee
core +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
secp256k1-frost: Minimal-dependency RFC 9591 FROST threshold signing for secp256k1
SoftwareXFlexible Round-Optimized Schnorr Threshold Signatures (FROST), standardized in IETF RFC 9591, allow a group of participants to jointly produce a compact Schnorr signature from distributed key shares.
Matteo Nardelli, Antonio Muci
doaj +1 more source