Results 171 to 180 of about 3,019,348 (325)

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Evaluation the effect of hydro-alcoholic extract of Portulaca oleracea and estradiol on pain threshold in female mice

Journal of Medicinal Plants, 2017
Background: There are many plant extracts which can modulate pain response. Also, studies represented modulatory effects of estradiol on pain. Objectives: The aim of the present study was to evaluate the effect of hydro alcoholic extract of Portulaca ...
Khaled Keshavarzi, Mojtaba Moradi, Esmaeil Khoshnam, Alvand Alvandi, Mansour Safaei Pour Zamani, Mohamad Fatahi, Azim Baziar   +6 more
doaj  

PainDECOG: Machine Learning-Based Identification of Pain Biomarkers from sEEG Signals [PDF]

arXiv
This study presents a systematic machine-learning approach for classifying acute pain from raw electrophysiological signals. We address binary and ternary classification tasks, leveraging Power-In-Band (PIB) and signal coherence as distinguishing features.
arxiv  

Neural Patterns of Social Pain in the Brain‐Wide Representations Across Social Contexts

Advanced Science, EarlyView.
Empathy arises from both physiological and social pain, yet their shared and context‐specific neural mechanisms remain unclear. Combining fMRI and multivariate pattern analysis, this study decodes overlapping empathy networks and distinct representations for social exclusion versus separation.
Xiaodong Zhang, Peng Qing, Qi Liu, Can Liu, Lei Liu, Xianyang Gan, Kun Fu, Chunmei Lan, Xinqi Zhou, Keith M. Kendrick, Benjamin Becker, Weihua Zhao   +11 more
wiley   +1 more source

Improving Pain Classification using Spatio-Temporal Deep Learning Approaches with Facial Expressions [PDF]

arXiv
Pain management and severity detection are crucial for effective treatment, yet traditional self-reporting methods are subjective and may be unsuitable for non-verbal individuals (people with limited speaking skills). To address this limitation, we explore automated pain detection using facial expressions.
arxiv  

Pain Tolerance Threshold: A Pilot Study of an Objective Measurement of Spinal Cord Stimulator Trial Results [PDF]

, 2000
Y. Eugene Mironer, Judson Somerville
openalex   +1 more source

Possibilities of attentional control of pain: influence of distractive Stroop task on pain threshold and pain tolerance [PDF]

, 2006
Attention has been shown to modulate pain perception, but the relationship between attention and pain perception is still not clearly understood. Two independent experiments were conducted to examine the influence of focusing attention away from painful ...
Ivanec, Dragutin, Kotzmuth, Ana, Pavin, Tea   +2 more
core   +1 more source

Microfluidics‐Based Microcarriers for Live‐Cell Delivery

Advanced Science, EarlyView.
In this review, recent advancements in microfluidics‐based microcarriers for live‐cell delivery are highlighted. The structural designs of microfluidic‐derived cell‐laden microcarriers are systematically categorized, emphasizing innovative approaches in the fabrication of microspheres, microfibers, and microneedles.
Zhonglin Fang, Xinyuan Yang, Chong Wang, Luoran Shang   +3 more
wiley   +1 more source

Features of central sensitisation in patients with shoulder pain : A feasibility study [PDF]

, 2019
Design. A case-control feasibility study, comparing people with unilateral shoulder pain and pain free controls. Background. Previous studies have suggested that central sensitisation (CS) may be present in people with shoulder pain, mostly based on ...
Herbland, Anthony, Lewis, Jeremy, van Griensven, Hubert   +2 more
core   +1 more source

Enhancing Grasping Function with a Thermoresponsive Ionogel Adhesive Glove for Patients with Rheumatic Diseases

Advanced Science, EarlyView.
This study presents a novel portable grasp‐assist glove, weighing only 47 g. The glove integrates smart adhesive pads and a hands‐free control interface based on IMU, designed to aid rheumatic patients with impaired hand function. The system enables switchable adhesion with independent control and detection of user release intent.
Shiqiang Wang, Shiqing Liu, Jingfeng Zhang, Zhouyang Yu, Yifan Shao, Cong Zhao, Jiahong Ma, Xin Fu, Mengqi Yang, Lie Chen, Mingjie Liu, Li Wen   +11 more
wiley   +1 more source