Results 11 to 20 of about 3,019,348 (325)

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls   +9 more
wiley   +1 more source

Pain threshold is reduced in depression [PDF]

open access: yesThe International Journal of Neuropsychopharmacology, 1998
Pain and depression may share common neurochemical substrates, therefore the study of pain sensation in depression might be valuable in the investigation of the pathophysiology of depression itself. In order to investigate the sensation of pain in depression, we measured pain threshold and sensory threshold by means of a dental tester, comparing a ...
Angela Di Muro   +7 more
openaire   +4 more sources

Pain science and practice as a ‘threshold concept’ within undergraduate and pre-registration physiotherapy education: a jewel of the curriculum?

open access: yesBMC Medical Education, 2023
Background Threshold concepts describe learning experiences that transform our understanding of a concept. Threshold concepts are variously: troublesome, transformative, irreversible, integrative and bounded.
Keith M. Smart
doaj   +1 more source

Scaling pain threshold with microRNAs [PDF]

open access: yesScience, 2017
Tuning pain with a defined microRNA ...
Laura Cassels, Yves-Alain Barde
openaire   +3 more sources

EFFECT OF HYPERTENSION ON PAIN THRESHOLD IN PATIENTS WITH CHRONIC PAIN

open access: yesCentral Asian Journal of Medical Hypotheses and Ethics, 2023
Introduction: Little is known about the relationship between pain and hypertension (HT). This study aimed to analyze the effect of HT on pain sensitivity in patients with chronic musculoskeletal pain complaints.
Tuba Tülay Koca   +4 more
doaj   +1 more source

Outcomes of a QST Protocol in Healthy Subjects and Chronic Pain Patients: A Controlled Clinical Trial

open access: yesBiomedicines, 2023
Chronic pain is an important cause of disability with a high burden to society. Quantitative sensory testing (QST) is a noninvasive multimodal method used to discriminate the function of nerve fibers.
Patrícia Dias   +3 more
doaj   +1 more source

Bell’s Palsy—Retroauricular Pain Threshold [PDF]

open access: yesMedicina, 2021
Background and objectives: Non-motor symptoms in the form of increased sensitivity are often associated with the onset of idiopathic Bell’s palsy (IBP). The aims were to determine whether the pain threshold in the retroauricular regions (RAR) in IBP patients and the time of its occurrence is related to IBP severity. Materials and Methods: The study was
Aleksandar Kopitović   +5 more
openaire   +4 more sources

Pain perception and migraine [PDF]

open access: yes, 2018
Background: It is well-known that both inter-and intra-individual differences exist in the perception of pain; this is especially true in migraine, an elusive pain disorder of the head.
Coppola, Gianluca   +6 more
core   +1 more source

PAIN THRESHOLD PARADOX IN SCHIZOPHRENIA: A NARRATIVE REVIEW BASED ON THE LASTEST NEUROSCIENCE [PDF]

open access: yes, 2023
Introduction: Pain is one of the basic defense responses of living organisms. Although the threshold for pain perception varies from person to person, there is no doubt that pain reduces a person’s quality of life.
Nagamine, Takahiko
core   +2 more sources

Exercise Increases Pressure Pain Tolerance but Not Pressure and Heat Pain Thresholds in Healthy Young Men [PDF]

open access: yes, 2017
Background: Exercise causes an acute decrease in the pain sensitivity known as exercise-induced hypoalgesia (EIH), but the specificity to certain pain modalities remains unknown.
Bartholomew   +39 more
core   +2 more sources

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