Results 251 to 260 of about 645,142 (352)

Neuropathy of the infraorbital area following rapid palatal expansion: A case report. [PDF]

Medicine (Baltimore)
Kim SM, Kho HS.
europepmc   +1 more source

Targeting the CMKLR1‐Mediated Signaling Rebalances Immunometabolism State in Middle‐Age Testicular Macrophages

Advanced Science, EarlyView.
In middle age, testicular CMKLR1⁺ macrophages exhibited a pro‐inflammatory immunometabolic profile, mediated by adipose signals associated with high BMI. However, inhibition of CMKLR1 signaling, either through Cmklr1 genetic ablation or treatment with a CMKLR1 antagonist peptide, can reverse this phenotype.
Zhendong Zhu, Feifei Du, Yang Liu, Jinchunzi Yang, Lei Ge, Tianxia Xiao, Mengxia Li, Jie Chen, Jia Tang, Yali Yang, Jian V. Zhang   +10 more
wiley   +1 more source

Intact endogenous pain inhibition in complex regional pain syndrome type 1. [PDF]

Pain Rep
Allmendinger F, Sirucek L, De Schoenmacker I, Scheuren PS, Brunner F, Schweinhardt P, Hubli M.   +6 more
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

No significant modulation of pressure pain sensitivity and cardioception after transauricular vagal nerve stimulation. [PDF]

Pain Rep
De Herde LMR, Frahm KS, Graff C, Dos Santos Nielsen T, Graven-Nielsen T, Siebner HR, Ciampi de Andrade D.   +6 more
europepmc   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

The role of GABAergic receptors in acute, subacute, and withdrawal syndrome on pain and seizure thresholds in mice: A connection to mitochondrial function and oxidative stress in the brain. [PDF]

Toxicol Rep
Jahani R, Pourbahram P, Seyedabadi M, Nasiri F, Mohammadi H.   +4 more
europepmc   +1 more source

Efficiency Recalibrates Social‐Emotional Trade‐Offs Behind Partner Choice in Direct Reciprocity through Intention‐Specific Neural Bases

Advanced Science, EarlyView.
Bridging the gap between two crucial mechanisms of cooperation, namely direct reciprocity and partner choice, this study reveals the neurocognitive bases underlying how individuals prioritize reciprocal partner when receiving help from multiple benefactors with diverse intentions and reciprocal efficiency. The efficiency‐driven reciprocal decisions are
Rui Liao, Xintong Li, Xuqi Liu, Yu Nan, Xiaolin Zhou, Xiaoxue Gao   +5 more
wiley   +1 more source

Minimal Clinically Important Difference and Patient Acceptable Symptom State for Patient-Reported Outcomes Following Common Arthroscopic Sports Surgeries of the Knee: A Systematic Review. [PDF]

Orthop J Sports Med
Kovacevic D, Sahi G, Lameire DL, Abbas A, Whelan DB, Theodoropoulos J, Dwyer T, Chahal J.   +7 more
europepmc   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source