Anthropological ReviewThe perception of pain, encompassing pain threshold and tolerance levels, is a complex phenomenon influenced by biological, psychological, and sociocultural factors.
Arpita Santra +3 more
doaj +1 more source
Modification of electrical pain threshold by voluntary breathing-controlled electrical stimulation (BreEStim) in healthy subjects. [PDF]
PLoS ONE, 2013 Pain has a distinct sensory and affective (i.e., unpleasantness) component. BreEStim, during which electrical stimulation is delivered during voluntary breathing, has been shown to selectively reduce the affective component of post-amputation phantom ...
Shengai Li +3 more
doaj +1 more source
The moderating factors of neuroticism and extraversion in pain anticipation [PDF]
, 2017 This study investigates the moderator relationship between three psychological variables on pain threshold and tolerance: pain anticipation, neuroticism and extraversion.
Birnie KA +7 more
core +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Experimental neck muscle pain impairs standing balance in humans [PDF]
Experimental Brain Research 192, 4 (2009) 723-9, 2009 Impaired postural control has been reported in patients with chronic neck pain of both traumatic and non-traumatic etiologies, but whether painful stimulation of neck muscle per se can affect balance control during quiet standing in humans remains unclear.
arxiv +1 more source
Body mass index and distribution of body fat can influence sensory detection and pain sensitivity. [PDF]
, 2017 BACKGROUND: The aim of this study was to investigate the influence of body fat percentage and its distribution on sensory detection and pain sensitivity responses to experimentally induced noxious stimuli in otherwise pain-free individuals.
Abou-Setta +44 more
core +1 more source
How different experimental models of secondary hyperalgesia change the nociceptive flexion reflex [PDF]
, 2021 In this neurophysiological study in healthy humans, we assessed how central sensitization induced by either high-frequency stimulation (HFS) or topical capsaicin application modulates features of the RIII reflex response.
Blockeel, A.J. +11 more
core +3 more sources
Establishment and biological characterization of radioresistant colorectal cancer cell lines
FEBS Open Bio, EarlyView.Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu +10 more
wiley +1 more source
Pain Relief in Older Adults Following Static Contractions is not Task-Dependent [PDF]
, 2012 Pain complaints increase with age. Exercise is frequently utilized for pain relief but the optimal exercise prescription to relieve pain is not clear.
Lemley, Kathy J. +4 more
core +2 more sources
Are Extracorporeal Shock Waves Just a Therapeutic Tool?
DiagnosticsBackground: Focused extracorporeal shock wave therapy (ESWT) has been successfully used to treat musculoskeletal conditions, but ESWT stimulates nociceptors, causing pain deep in the tissue during treatment.
Bernardo Gialanella +7 more
doaj +1 more source