Results 171 to 180 of about 1,445,591 (343)

Differential Threshold for Compression Modulus [PDF]

, 1939
G. W. Scott Blair, F. M. V. Coppen
openalex   +1 more source

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

Molecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker, Elysia Sarsam, Stuart J. Conway, Ester M. Hammond   +3 more
wiley   +1 more source

Is the Threshold Audiogram Sufficient for Determining Hearing Capacity? [PDF]

, 1943
Edmund Prince Fowler
openalex   +1 more source

Cluster-extent based thresholding in fMRI analyses: Pitfalls and recommendations

NeuroImage, 2014
Choong-Wan Woo, A. Krishnan, T. Wager
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Segmentation of White Blood Cells From Microscopic Images Using a Novel Combination of K-Means Clustering and Modified Watershed Algorithm

Journal of Medical Signals and Sensors, 2017
Recognition of white blood cells (WBCs) is the first step to diagnose some particular diseases such as acquired immune deficiency syndrome, leukemia, and other blood-related diseases that are usually done by pathologists using an optical microscope. This
Narjes Ghane, Alireza Vard, Ardeshir Talebi, Pardis Nematollahy   +3 more
doaj  

Variability of the Absolute Auditory Threshold: A Psychophysical Study [PDF]

, 1953
George Herman
openalex   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Comprehensive evaluation of optimization algorithms for medical image segmentation. [PDF]

Sci Rep
Al-Najdawi NA, Al-Shawabkeh AF, Tedmori S, Ikhries II, Dorgham O.   +4 more
europepmc   +1 more source

The menstrual cycle of the primates - X—The oestrone threshold of the uterus of the rhesus monkey

, 1937
Solly Zuckerman
openalex   +1 more source