Results 221 to 230 of about 250,897 (267)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Improved COOT optimization: An approach to multilevel thresholding in image segmentation. [PDF]

Sci Rep
Singh S, Singh H, Mousavirad SJ, Oliva D, Hussien AG, Abualigah L.   +5 more
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Deep neural network-based robust framework for automated skin lesion segmentation and analysis. [PDF]

Digit Health
Mehdar KM, Soomro TA, Ali A, Bin Ubaid F, Irfan M, Halawani HT, Mashraqi AM, Mohammed Elshafie SE, Asiri AA, Abdelkafi Magzoub M.   +9 more
europepmc   +1 more source

Deep learning models to map osteocyte networks from confocal microscopy can successfully distinguish between young and aged bone. [PDF]

PLoS Comput Biol
Vetter SD, Schurman CA, Alliston T, Slabaugh G, Verbruggen SW.   +4 more
europepmc   +1 more source

gDAIS: A Global Analysis Application for Obtaining Confidence in FLIM. [PDF]

Proc SPIE Int Soc Opt Eng
Mattu N, Su J, Yonas S, Liu Y, Alspaugh G, Qazi S, Slamani A, Link KA, Penjweini R, Combs CA, Sackett D, Knutson JR.   +11 more
europepmc   +1 more source

Aerial image segmentation using multilevel thresholding based on multi strategy Osprey optimization algorithm. [PDF]

Sci Rep
Abd Elaziz M, Al-Betar MA, Ewees AA, Al-Qaness M.   +3 more
europepmc   +1 more source