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Inherited Platelet Disorders During Pregnancy and Delivery: Overview of Management Strategies and Emerging Therapeutic Considerations [PDF]

Hematology Reports
Inherited platelet disorders (IPDs) comprise a heterogeneous group of rare conditions that present particular challenges during pregnancy, with bleeding risk increasing during labor and the immediate postpartum period. These disorders require coordinated,
Victor Zibara, Nicoletta Machin
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Glanzmann’s thrombasthenia: A nightmare for hernia surgeons [PDF]

Journal of Minimal Access Surgery
Glanzmann’s thrombasthenia is a rare inherited disorder affecting one in one million. It is characterised by a lack of platelet aggregation due to a defect in the platelet membrane receptor complex (αIIb/βIIIa), which mediates the aggregation of ...
Jignesh Gandhi, Aarsh Gajjar, Pravin Shinde, Yogesh Takalkar   +3 more
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Genetic classification and confirmation of inherited platelet disorders: current status in Korea [PDF]

Clinical and Experimental Pediatrics, 2020
Inherited platelet disorders (IPDs), which manifest as primary hemostasis defects, often underlie abnormal bleeding and a family history of thrombocytopenia, bone marrow failure, hematologic malignancies, undefined mucocutaneous bleeding disorder, or ...
Ye Jee Shim
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Glanzmann thrombasthenia—A not so rare platelet function disorder in Pakistan

Global Pediatrics, 2022
Objectives: To determine the prevalence, clinical manifestations and laboratory findings of Pakistani Glanzmann Thrombasthenia patients and to assess the treatment received by these patients. Materials and Method: This cross-sectional study examined 2542
Rafia Mahmood, Hamid Saeed Malik, Maria Khan, Sadia Ali, Asad Mahmood, Saleem Ahmed Khan   +5 more
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Current Knowledge on Inherited Platelet Function Disorders

Clinical Pediatric Hematology-Oncology, 2020
Inherited platelet function disorders (IPFDs) are rare and underdiagnosed in individuals with clinically significant bleeding diathesis. IPFDs are classified according to the causative molecular defects involved in the process of primary hemostasis of ...
Nani Jung, Ye Jee Shim
doaj   +1 more source

Total Extraction as a Treatment for Anaemia in a Patient of Glanzmann's Thrombasthenia with Chronic Gingival Bleed: Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Glanzmann’s Thrombasthenia (GT) is a rare autosomal recessive bleeding disorder affecting the megakaryocyte lineage and is characterized by lack of platelet aggregation on stimulation.
Abhishek Ghosh, Saurabh Kumar, Rabin Chacko, Arun Paul Charlu   +3 more
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Glanzmann Thrombasthenia: A Case Report of a Rare Inherited Coagulation Disorder Presenting with Traumatic Head Injury

European Medical Journal Hematology, 2021
This case study deals with a 32-year-old Indian male patient who presented with a traumatic head injury in the hospital, experienced uncontrolled bleeding after conducting surgery, and was eventually diagnosed with Glanzmann thrombasthenia.
Vishal Chakati, Durga Prasad Bukka, Srinivas Rao Erigaisi, Shyam Sunder Anchuri   +3 more
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Thromboelastography with platelet mapping to guide anesthetic management of emergency cesarean delivery in a patient with thrombasthenia: a case report

JA Clinical Reports, 2023
Background Perinatal management of congenital platelet dysfunction represents a challenge. One of the major concerns is whether neuraxial anesthesia can be applicable for cesarean delivery. We present a patient with thrombasthenia who underwent emergency
Chieko Akinaga, Shingo Kawashima, Yuji Suzuki, Masako Matsumoto, Yoshiki Nakajima   +4 more
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Management of Glanzmann's Thrombasthenia – Guidelines based on an expert panel consensus from gulf cooperation council countries

Journal of Applied Hematology, 2019
Glanzmann thrombasthenia is a rare disorder, due to quantitative and/or qualitative abnormalities of the platelet integrin αIIbβ3 and/or αIIbβ3. Although it is considered a rare disorder with a global incidence of 1/1,000,000 population, the case is ...
Ahmad Tarawah, Tarek Owaidah, Naima Al-Mulla, Muhammad Faisal Khanani, Jehan Elhazmi, Muneer Albagshi, Yaser Wali, Shikah AlMohareb, Abdulkareem Almomen   +8 more
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Glanzmann's thrombasthenia – A rare case report of spontaneous gingival bleeding

Journal of Indian Academy of Oral Medicine and Radiology, 2018
Glanzmann's thrombasthenia is a rare congenital bleeding disorder which is associated with mutations in the genes encoding glycoproteins, gpIIb or gpIIIa resulting in platelet dysfunction.
Vijayalakshmi Venkat, Sruti Kalluri, Satheesha Reddy Bandalore Hanumantha   +2 more
doaj   +1 more source