Results 101 to 110 of about 28,502 (229)

What Is Your Diagnosis? Blood Smear From a North American Beaver (Castor canadensis)

open access: yes
Veterinary Clinical Pathology, EarlyView.
Lilani Munasinghe   +4 more
wiley   +1 more source

A Case Illustrating Challenges: Early‐Onset Signet Ring Cell Rectal Carcinoma With Fulminant Peritoneal Progression

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Signet ring cell carcinoma (SRCC) of the rectum is a rare histologic subtype and is often associated with aggressive behavior and poor outcomes, particularly in young patients. We report a 19‐year‐old male who presented with acute intestinal obstruction and was diagnosed with rectal SRCC, radiologically staged as cT2N1bM0, acknowledging the ...
Shivraj Sharma   +6 more
wiley   +1 more source

Manifestations and Related Risk Factors of Thrombocyte Abnormalities in HIV-Positive Patients Before and After the Initiation of ART

open access: yesInfection and Drug Resistance, 2021
Bei Li,1 Leidan Zhang,2 Ying Liu,1 Jing Xiao,2 Xinyue Wang,2 Yuqing Wei,1 Lina Fan,3 Yujiao Duan,1 Guoli Li,4 Yaxian Kong,4 Hongxin Zhao1 1Clinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing ...
Li B   +10 more
doaj  

Ten‐Year Outcome of a Patient With Concurrent Pelvic Myeloid Sarcoma and Underlying Chronic Myeloid Leukaemia in Chronic Phase: A Case Report and Literature Review

open access: yesCancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Myeloid sarcoma is a rare solid tumour of immature myeloid precursors occurring in an extramedullary site. It often presents significant diagnostic and therapeutic challenges to clinical haematologists. Case We describe a previously healthy patient who presented simultaneously with hyperleucocytic chronic myeloid leukaemia in ...
Kar Ying Yong   +3 more
wiley   +1 more source

Identification of MPL R102P Mutation in Hereditary Thrombocytosis

open access: yesFrontiers in Endocrinology, 2017
The molecular basis of hereditary thrombocytosis is germline mutations affecting the thrombopoietin (TPO)/TPO receptor (MPL)/JAK2 signaling axis. Here, we report one family presenting two cases with a mild thrombocytosis.
C. Bellanné-Chantelot   +5 more
semanticscholar   +1 more source

A Freshwater Pearl Mussel Polysaccharide Alleviates Inflammatory Pain by Targeting Peripheral Cytokines and Spinal Astroglial NLRP3/GFAP Responses

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Mussel polysaccharide (MP), a novel food resource from pearl mussels, alleviates inflammatory pain in rats in a dose‐dependent manner. It acts by dually inhibiting peripheral inflammation (reducing paw swelling and pro‐inflammatory cytokines) and spinal neuroinflammation via the NLRP3 and astrocyte pathway.
Chen Hu   +8 more
wiley   +1 more source

Unraveling the role of TP53 mutations in myeloproliferative neoplasms: Molecular mechanisms of leukemic transformation

open access: yesHemaSphere, Volume 10, Issue 3, March 2026.
Abstract TP53 mutations are found in over 50% of tumor types, including myeloproliferative neoplasms (MPNs). MPNs are characterized by a chronic phase, which may progress to secondary acute myeloid leukemia (sAML). Here, we discuss the physiological functions of p53 in hematopoiesis and its deregulation in MPNs.
Suzana da Silva‐Benedito   +6 more
wiley   +1 more source

Complete Blood Count Profile in Steady State Sickle Cell Disease Patient: A Systematic Review and Meta‐Analysis

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Sickle cell disease is a genetic disorder whose pathophysiology is primarily characterized by vasoocclusive crises and hemolytic crises. The stationary phase describes the interval between two vasoocclusive crises. The aim of this systematic review and meta‐analysis was to synthesize studies published over the past two ...
Josué Louokdom Simo   +5 more
wiley   +1 more source

THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)

open access: yesCiência Animal Brasileira, 2019
Thrombocytosis refers to the increase in number of platelets per microliter (μL) of blood. Platelet counts greater than 1,000,000/μL may be associated with clinical signs of bleeding or thrombosis.
Marcela Natacha Aparecida Rocha   +5 more
doaj  

Successful Treatment of Paranasal Sinus Metastasis From Renal Cell Carcinoma With Immune Checkpoint Inhibitors and Radiotherapy: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Renal cell carcinoma (RCC) metastasis to the paranasal sinuses is rare and lacks standard treatment, particularly for unresectable tumors. We report a case of sphenoid sinus metastasis with sarcomatoid differentiation successfully managed with radiation therapy and immunotherapy.
Shota Yamada   +7 more
wiley   +1 more source

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