Results 71 to 80 of about 36,142 (215)

Thrombophilia work-up and clinical outcomes in Indian patients with unprovoked venous and arterial thrombosis aged 18-50 years

Bleeding, Thrombosis and Vascular Biology
Background: The prevalence of thrombophilia in patients with unprovoked thrombotic events varies across populations, justifying the need for region-specific data to guide appropriate testing strategies.
Monisha Harimadhavan, Bharath Ram, Karthick R G, Devi Prasad Shetty, Shilpa Prabhu, Nataraj K S, Akshatha Nayak, Sharat Damodar   +7 more
doaj   +1 more source

Neonates born at term with periventricular haemorrhagic infarction: Risk factors and clinical presentation

Developmental Medicine &Child Neurology, EarlyView.
This case series describes infants born near term with periventricular hemorrhagic infarction (PVHI), highlighting seizures as a common early symptom. Neonatal complications during delivery and pro‐thrombotic genetic mutations were slightly more common. MRI‐classified involvement was predominantly in the caudate vein territory.
Aleksandra Zaykova, Jeroen Dudink, Floris Groenendaal, Maarten H. Lequin, Manon J.N.L. Benders, Maria Luisa Tataranno, Elise Roze   +6 more
wiley   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Thrombotic variables and risk of idiopathic venous thromboembolism in women aged 45-64 years - Relationships to hormone replacement therapy [PDF]

, 2000
Hormone replacement therapy (HRT) has been shown to increase the relative risk of idiopathic venous thromboembolism (VTE) about threefold in several observational studies and one randomised controlled trial. Whether or not this relative risk is higher in
Daly, E., Gough, P., Lowe, G., Rumley, A., Vessey, M., Woodward, M.   +5 more
core  

Inherited thrombophilia secondary to protein S deficiency associated with ischemic stroke. Case report [PDF]

Romanian Journal of Neurology, 2016
Thrombophilia is characterized by an increased tendency to arterial and venous thrombus formation. Inherited thrombophilia can be secondary to protein S deficiency.
Diana Matcau, Claudia Barsan, Traian Flavius Dan, Camelia Barbusi, Any Docu Axelerad, Dragos Catalin Jianu   +5 more
doaj   +1 more source

Thrombin Generation in Pediatric Haemophilia A Patients on Extended Half‐Life FVIII versus Non‐FVIII Therapies

Haemophilia, EarlyView.
ABSTRACT Introduction The therapeutic landscape for patients with haemophilia A (PwHA) is rapidly evolving with the introduction of extended half‐life FVIII (EHL‐FVIII) and non‐FVIII therapies that mimic FVIII, such as emicizumab (EMI). Monitoring non‐factor therapies in the laboratory poses challenges; however, the thrombin generation assay (TGA) can ...
Jessica Garcia, Sean G. Yates, Ravi Sarode, Guy Young, Ayesha Zia   +4 more
wiley   +1 more source

Polymorphisms of plasminogen activator inhibitor-1, angiotensin converting enzyme and coagulation factor XIII genes in patients with recurrent spontaneous abortion [PDF]

, 2011
We investigated polymorphisms of plasminogen activator inhibitor-1 (PAI-1), angiotensin converting enzyme (ACE ) and coagulation factor XIII (FXIII) genes and their association with recurrent spontaneous abortion (RSA) in Iranian patients and normal ...
Aarabi, M., Aarabi, M., Akhondi, M.A., Arefi, S., Memariani, T., Modarressi, M.H., Zadeh, S.H.   +6 more
core  

Prevalence of thrombophilia factors in patients with May-Thurner syndrome and left common iliac vein thrombosis [PDF]

, 2010
BACKGROUND: The relationship between deep venous thrombosis and thrombophilia has been little studied in patients with left common iliac vein compression, clinically known as May-Thurner syndrome.
Cury Filho, José Mussa, Gress, Marcus, Marques, Marcos Arêas, Massière, Bernardo, Silveira, Paulo Roberto Mattos Da [UNIFESP], Vescovi, Alberto, Vieira, Rafael Dias, Von Ristow, Arno   +7 more
core   +3 more sources

Stillbirth in pregnancies with flat OGTT: Placental clues to occult maternal dysmetabolism

International Journal of Gynecology &Obstetrics, EarlyView.
Emma Bertucci, Alessandra Danieli, Francesco Ricciardiello, Isabella Neri, Francesca Monari, Alessandro D. Genazzani, Gaetano Bulfamante, Antonio La Marca, Laura Botticelli, Fabio Facchinetti, Laura Avagliano   +10 more
wiley   +1 more source

Assessing the Impact of the 2021 VWD Guidelines on the Diagnosis/Management of Low VWF Patients

Haemophilia, EarlyView.
ABSTRACT Introduction The 2021 ASH/ISTH/NHF/WFH VWD diagnosis guidelines recommend Type 1 VWD diagnoses for patients with (a) VWF <0.30 IU/mL or (b) ‘Low VWF’ 0.30–0.50 IU/mL with the presence of abnormal bleeding. This recommendation recategorizes ‘Low VWF’ patients with abnormal bleeding into Type 1 VWD.
Michael Dong, Joanna Larson, Sepideh Saroukhani, Miguel Escobar, Lakshmi Srivaths   +4 more
wiley   +1 more source