Should thrombopoietin receptor agonists be used for chemotherapy-induced thrombocytopenia? [PDF]
Research and Practice in Thrombosis and HaemostasisChemotherapy-induced thrombocytopenia (CIT) is a common complication of cancer therapy for solid tumors that results in increased bleeding risk and chemotherapy dose reductions, treatment delays, and agent discontinuation.
Hanny Al-Samkari
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Thrombopoietin Receptor Agonists in Post-Hematopoietic Cell Transplantation Complicated by Prolonged Thrombocytopenia: A Comprehensive Review [PDF]
ImmunoTargets and TherapyAbdelrahman Elsayed,1 Basant Elsayed,1 Mohamed Elmarasi,1 Ahmed Adel Elsabagh,1 Engy Elsayed,2 Ibrahim Elmakaty,1 Mohamed Yassin2,3 1Department of Medical Education, Hamad Medical Corporation, Doha, Qatar; 2College of Medicine, Qatar University, Doha ...
Elsayed A +6 more
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Impact of Thrombopoietin Receptor Agonists on Pathophysiology of Pediatric Immune Thrombocytopenia [PDF]
Current Issues in Molecular BiologyImmune thrombocytopenia (ITP) in pediatric patients is a common cause of isolated thrombocytopenia. Various pathophysiological mechanisms are implicated in ITP pathogenesis, including the production of autoantibodies against components of platelets (PLTs)
Paschalis Evangelidis +3 more
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Knowledge map of thrombopoietin receptor agonists: A bibliometric analysis [PDF]
HeliyonBackground: Thrombopoietin receptor agonists (TPO-RAs) have been widely used to treat thrombocytopenia, however, a scientometric profile of TPO-RAs research is lacking.
Rong Hu, Songbin Guo, Min Liu
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Use of thrombopoietin receptor agonists in childhood immune thrombocytopenia [PDF]
Frontiers in Pediatrics, 2015 Most children with immune thrombocytopenia (ITP) will have spontaneous remission regardless of therapy, while about 20% will go on to have chronic ITP.
Angelica Maria Garzon +2 more
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Second-line administration of thrombopoietin receptor agonists in immune thrombocytopenia: Italian Delphi-based consensus recommendations [PDF]
Therapeutic Advances in Hematology, 2021 Introduction: In patients with primary immune thrombocytopenia (ITP), a short course of steroids is routinely given as first-line therapy. However, the response is often transient and additional therapy is usually needed. Thrombopoietin receptor agonists
Monica Carpenedo +14 more
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Pharmacoeconomic analysis of thrombopoietin receptor agonists in the treatment of chronic idiopathic thrombocytopenic purpura in adults [PDF]
Качественная клиническая практика, 2018 Actuallity. Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease caused by the production of antibodies to the platelet and megakaryocytes membrane structure, which causes to increase the platelet destruction, but also inadequate ...
E. A. Pyadushkina +3 more
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Российский журнал гастроэнтерологии, гепатологии, колопроктологииAim: to review the pathogenesis of thrombocytopenia and possible ways of its correction in patients with liver cirrhosis before elective surgical interventions or invasive procedures to optimize clinical practice.Key points.
T. A. Deeva +2 more
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Eltrombopag use in surgical procedures in inherited thrombocytopenia: expanding the role of thrombopoietin-receptor agonists [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Inherited thrombocytopenias (ITs) are a group of rare disorders characterized by low platelet counts and variable bleeding risk. Surgical procedures in these patients often require transient platelet elevation.
Miguel de Oliveira +3 more
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Biologics: Targets & Therapy, 2009 Ara Metjian1, Charles S Abrams21Department of Medicine, Duke University Medical Center, Durham, NC, USA; 2Department of Medicine, University of Pennsylvania, Philadelphia, PA, USAAbstract: Decades of basic science and clinical research have led to an ...
Ara Metjian, Charles S Abrams
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