Results 271 to 280 of about 116,907 (303)

Syndromes of Thrombotic Microangiopathy.

Medical Clinics of North America, 2017
Thrombotic thrombocytopenia purpura (TTP) and the hemolytic uremic syndrome (HUS) are rare thrombotic microangiopathies that can be rapidly fatal. Although the acquired versions of TTP and HUS are generally highest on this broad differential, multiple rarer entities can produce a clinical picture similar to TTP/HUS, including microangiopathic hemolysis,
J. Shatzel, Jason A Taylor
semanticscholar   +4 more sources

Thrombotic Microangiopathies

New England Journal of Medicine, 2002
The thrombotic microangiopathies (TMA) are a group of diseases associated with microangiopathic hemolytic anemia, thrombocytopenia, and end-organ dysfunction. These seemingly disparate entities share in common a pathogenic mechanism involving endothelial injury and thrombus formation.
Daniel, Halevy, Jai, Radhakrishnan, Glen, Markowitz, Gerald, Appel   +3 more
  +9 more sources

Thrombotic microangiopathy, hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: Rare manifestations of Russell’s viper (Daboia russelii) envenoming in Sri Lanka

, 2021
Background: Russell’s viper (Daboia russelii) of Family Viperidae is a highly venomous snake in Sri Lanka and is responsible for the most snakebite deaths. It commonly causes coagulopathy and neuroparalysis. Thrombotic microangiopathy (TMA) including the
R. Rathnayaka, P. Ranathunga, S. Kularatne   +2 more
semanticscholar   +1 more source

A pilot trial of prophylactic defibrotide to prevent serious thrombotic microangiopathy in high‐risk pediatric patients

Pediatric Blood & Cancer, 2022
Transplant‐associated thrombotic microangiopathy (TA‐TMA) is an endothelial injury complication of hematopoietic stem cell transplant (HSCT) leading to end‐organ damage and high morbidity and mortality.
C. Higham, K. Shimano, Alexis Melton, S. Kharbanda, Julia Chu, Jasmeen S Dara, Lena E. Winestone, M. Hermiston, James N. Huang, C. Dvorak   +9 more
semanticscholar   +1 more source

Thrombotic microangiopathy in patients with malignant hypertension.

Nephrology, Dialysis and Transplantation, 2022
BACKGROUND Thrombotic microangiopathy (TMA) is a complication of malignant hypertension (mHTN) attributed to the high levels of blood pressure (BP). However, no studies have investigated in patients with mHTN of different etiologies whether the presence ...
T. Cavero, P. Auñón, F. Caravaca-Fontán, Hernando Trujillo, Emilia Arjona, E. Morales, E. Guillen, M. Blasco, C. Rabasco, M. Espinosa, M. Blanco, Catuxa Rodríguez-Magariños, M. Cao, A. Ávila, A. Huerta, E. Rubio, V. Cabello, X. Barros, E. Goicoechea de Jorge, S. Rodríguez de Córdoba, M. Praga   +20 more
semanticscholar   +1 more source

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Complicated by Thrombotic Microangiopathy with Posterior Reversible Encephalopathy Syndrome Successfully Treated with Eculizumab: A Case Report.

Modern Rheumatology Case Reports, 2022
Thrombotic microangiopathy is characterised by endothelial cell injury, intravascular platelet-fibrin thrombi, and vascular damage, leading to acute kidney injury, thrombocytopenia, and microangiopathic haemolytic anaemia.
Fumiya Kitamura, M. Yamaguchi, Minori Nishimura, Takayuki Katsuno, Mayumi Ito, H. Sugiyama, S. Iwagaitsu, H. Nobata, H. Kinashi, Takuji Ishimoto, S. Banno, Yasuhiko Ito   +11 more
semanticscholar   +1 more source

Thrombotic Microangiopathies

Ugeskrift for laeger, 2009
The thrombotic microangiopathic diseases, which include acquired and congenital TTP and HUS, are most frequently acute disease entities. Untreated, these diseases are associated with a lethal course in many cases. Deficiency of the von Willebrand cleaving enzyme, ADAMTS13, is a decisive pathophysiological defect in most cases of thrombotic ...
Cynthia C. Nast, Sharon G. Adler
openaire   +4 more sources

Thrombotic microangiopathies

Seminars in Arthritis and Rheumatism, 2014
To review the clinical features and pathophysiologic mechanisms of the thrombotic microangiopathies (TMAs) including acquired and congenital thrombotic thrombocytopenic purpura (TTP), Shiga toxin-induced and atypical (non-Shiga toxin-induced) hemolytic uremic syndrome (HUS), and the TMAs associated with pregnancy, drugs, and organ transplantation ...
openaire   +4 more sources

Severe COVID‐19 infection and thrombotic microangiopathy: success does not come easily

British Journal of Haematology, 2020
Recent evidence suggests that signs and symptoms of severe COVID-19 infection resemble more the pathophysiology and phenotype of complement-mediated thrombotic micoangiopathies (TMA), rather than sepsis-induced coagulopathy or disseminated intravascular ...
E. Gavriilaki, R. Brodsky
semanticscholar   +1 more source

Thrombotic microangiopathy

Transfusion and Apheresis Science, 2011
Thrombotic microangiopathy (TMA) is a histopathological feature of various diseases including thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). There are many secondary causes of TMA, many of them could mimic TTP or HUS. This article presents a short overview on TMA.
M, Mörtzell, G, Berlin, T, Nilsson, C G, Axelsson, M, Efvergren, J, Audzijoni, A, Griskevicius, J, Ptak, M, Blaha, H, Tomsova, G M, Liumbruno, P, Centoni, E, Newman, S, Eloot, A, Dhondt, J, Tomaz, V, Witt, G, Rock, B, Stegmayr   +18 more
openaire   +2 more sources