Results 281 to 290 of about 116,907 (303)

Thrombotic microangiopathy

European Journal of Internal Medicine, 2000
The term 'thrombotic microangiopathy' (TMA) describes syndromes of microangiopathic hemolytic anemia, thrombocytopenia, and variable signs of organ impairment, due to platelet aggregation in the microcirculation. The term 'hemolytic uremic syndrome' (HUS) has entered clinical use to describe childhood cases of TMA dominated by renal impairment, while ...
, Pisoni, , Remuzzi
openaire   +2 more sources

A case of thrombotic microangiopathy/microangiopathies

Blood Coagulation & Fibrinolysis, 2014
We report a case of Streptococcus pneumonia sepsis-associated disseminated intravascular coagulation (DIC) with features of acute renal failure and microvascular thrombosis characterized by skin purpura and bilateral foot necrosis. The persistence of laboratory features of microangiopathic hemolytic anemia despite aggressive correction of DIC ...
Rohit Kumar, Zhineng J. Yang, Roy E. Smith   +2 more
openaire   +3 more sources

Bevacizumab-associated thrombotic microangiopathy treated with eculizumab: A case series and systematic review of the literature.

Clinical Nephrology, 2021
BACKGROUND Bevacizumab is a recombinant monoclonal antibody against the vascular endothelial growth factor A (VEGF-A) ligand that is used in the management of various solid malignancies.
Rachel Hilburg, A. S. Geara, M. Qiu, M. Palmer, Elaine Y. Chiang, R. Burger, Jonathan J. Hogan   +6 more
semanticscholar   +1 more source

Thrombotic Microangiopathy in Cancer

Seminars in Thrombosis and Hemostasis, 2018
AbstractThrombotic microangiopathy (TMA) is a rare but often devastating complication of cancer and cancer treatment. The syndrome is defined by thrombocytopenia (i.e., a platelet count of < 150,000/mcL or > 30% decrease from baseline), microangiopathic hemolytic anemia, and some evidence of organ damage.
openaire   +4 more sources

Familial Thrombotic Microangiopathy

QJM: An International Journal of Medicine, 1985
A family in which there were two certain and three possible cases of thrombotic microangiopathy in two generations is presented. All afflicted members studied presented with acute renal failure, and accelerated hypertension. No abnormal platelet-aggregating activity could be identified in the plasma of asymptomatic family members or in the surviving ...
Merrill Rh, Knupp Cl, Jennette Jc
openaire   +3 more sources

Pretransplant Genetic Susceptibility: Clinical Relevance in Transplant-Associated Thrombotic Microangiopathy

Thrombosis and Haemostasis, 2020
Transplant-associated thrombotic microangiopathy (TA-TMA) is a life-threatening complication of allogeneic hematopoietic cell transplantation (HCT).
E. Gavriilaki, T. Touloumenidou, I. Sakellari, I. Batsis, D. Mallouri, Fotis Psomopoulos, M. Tsagiopoulou, M. Koutra, E. Yannaki, A. Papalexandri, P. Taylor, E. Nikolousis, M. Stamouli, A. Holbro, I. Baltadakis, M. Liga, A. Spyridonidis, P. Tsirigotis, N. Charchalakis, D. Tsakiris, R. Brodsky, J. Passweg, K. Stamatopoulos, A. Anagnostopoulos   +23 more
semanticscholar   +1 more source

Thrombotic microangiopathy in pregnancy

Thrombosis Research, 2009
Following the initial reports by Moschowitz in 1925 [1] and by Baehr et al. in 1936 [2], Singer [3] and Gasser [4] suggested the terms of “thrombotic thrombocytopenic purpura, TTP” and of “hemolytic uremic syndrome, HUS” to describe related disorders consisting of Coombs’ negative hemolytic anemia, thrombocytopenia, and renal failure.
Annalisa Fattorini, L. Crippa, Armando D'Angelo   +2 more
openaire   +3 more sources

A New Paradigm for Renal Thrombotic Microangiopathy.

Seminars in diagnostic pathology, 2020
Thrombotic microangiopathy (TMA) is characterized by thrombocytopenia and microangiopathic hemolytic anemia, results from acute and/or chronic endothelial cell injury, and often manifests with kidney dysfunction. TMA can be observed in a wide spectrum of
A. Gallan, A. Chang
semanticscholar   +1 more source

[Thrombotic microangiopathy].

Der Internist, 2013
Thrombotic microangiopathy should be suspected every time the combination of microangiopathic hemolytic anemia without a coexisting cause, thrombocytopenia as well as renal and/or neurologic abnormalities occurs. The general term thrombotic microangiopathy includes different subtypes of the disease leading to abnormalities in multiple organ systems by ...
Ganser, A., Kielstein, J. T., Beutel, G.
openaire   +2 more sources

Thrombotic Microangiopathy in the Cancer Patient

Acta Haematologica, 2001
Thrombotic microangiopathy, manifesting as thrombotic thrombocytopenic purpura (TTP) or hemolytic uremic syndrome, is a common complication in cancer patients. It shares the pathogenic microvascular occlusive lesion and many clinical manifestations as the classical TTP, but the spectrum of complications varies widely.
Leo I. Gordon, Hau C. Kwaan
openaire   +3 more sources