Results 131 to 140 of about 167,463 (313)
Pathogenic PF4/Polyanion ELISA‐Negative Antibodies in HIT
American Journal of Hematology, EarlyView.ABSTRACT Background Platelet factor 4‐polyanion enzyme‐linked immunosorbent assays (ELISAs) are considered highly sensitive for diagnosing heparin‐induced thrombocytopenia (HIT), such that current practice guidelines recommend use of ELISA‐negative results to exclude HIT.
Adam J. Kanack +25 more
wiley +1 more source
Effect of Shear Rate on Thrombus Growth
, 2010 In this study micro and nano scale measurement techniques are applied to platelet studies and determination of factors in platelet aggregation and thrombus formation.
Andreas Fouras +2 more
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg +9 more
wiley +1 more source
Blood, 2014 In this issue of Blood , Ivanciu et al, Welsh et al, Tomaiuolo et al, and Stalker et al, in a series of studies from the University of Pennsylvania, use intravital microscopy to evaluate how thrombi form following vascular injury and reveal unexpected interactions and physical forces that ...
openaire +3 more sources
, 1995 The presence of residual mural thrombus (MT) predisposes to recurrent thrombotic vessel occlusion. To compare the benefits of different antithrombotic and anti platelet agents we studied the growth of thrombus on a preexisting mural thrombus in a well ...
Badimon, Juan J. +5 more
core +1 more source
Animal models of chronic thromboembolic pulmonary hypertension
Animal Models and Experimental Medicine, EarlyView.Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu +5 more
wiley +1 more source
Porcine kidney xenotransplantation: From primate models to clinical reality
Animal Models and Experimental Medicine, EarlyView.In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
When a Thrombus Is Not a Thrombus: To Anticoagulate or Not to Anticoagulate [PDF]
D65. THROMBUS AND TUMORS: CASE REPORTS, 2020 B. Wiese, K. Hess
openaire +1 more source
Animal Models and Experimental Medicine, EarlyView.Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley +1 more source
, 2016 In acute ischemic stroke (AIS) management, CT-based thrombus density has been associated with treatment success. However, currently used thrombus measurements are prone to inter-observer variability and oversimplify the heterogeneous thrombus composition.
van Oostenbrugge, Robert Jan +1 more
core +2 more sources