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Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

THROTTLE CONTROL OF THE HYDRAULIC DRIVE BY MEANS OF A SEQUENTIAL THROTTLE

COLLECTION OF SCIENTIFIC PAPERS, 2023
The article is devoted to the problem of solving the problem of regulating the speed of the output link of the hydraulic drive by means of a sequential throttle with the discharge of the working fluid into the storage tank, bypassing the hydraulic motor.
S.V. Teplyakova   +2 more
openaire   +1 more source

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