Results 61 to 70 of about 33,782 (335)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Study on the effect of the pressure characteristics of the cone throttle on the cavitation

open access: yesThe Journal of Engineering, 2018
According to the cone-type throttle valve is prone to cavitation, resulting in the reduction in the performance of the cone throttle valve. Here, a visual experimental platform for hydraulic cavitation is built, and the cavitation number of the conical ...
Jian Zhang   +3 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Design and implementation of a rudder and propulsion control system for a USV prototype for the Hydrocontest international competition

open access: yesDerrotero, 2018
This paper describes the considerations taken into account in order to design and build an electronic control system to be used on an Unmanned Surface Vehicle (USV), in an effective, versatile and economic way, using Commercial Off-The-Shelf elements ...
Juan Pablo Gutiérrez Bucheli   +1 more
doaj  

Asymmetric modelling and control of an electronic throttle [PDF]

open access: yesInternational Journal of Numerical Modelling: Electronic Networks, Devices and Fields, 2015
SummaryThis paper presents an improved model for an automotive electronic throttle inspired on the behaviour observed in real‐time experiments. Due to a number of issues, particularly the return‐spring, the performance of the throttle valve depends on whether it is opening or closing.
Pujol Vázquez, Gisela   +3 more
openaire   +4 more sources

Non-lane-discipline-based car-following model incorporating the electronic throttle dynamics under connected environment

open access: yesNonlinear dynamics, 2017
This study proposes a new car-following model considering the effects of the electronic throttle dynamics to capture the characteristics of connected autonomous vehicular traffic flow without lane discipline.
Yongfu Li   +4 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Test bench for throttle flow dividers-adders [PDF]

open access: yesBIO Web of Conferences
The control of modern mobile machinery and technological equipment increasingly relies on the utilization of multi-circuit and branched hydraulic drives.
Rybak Alexander   +6 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

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