Dynamic Modelling and Predictive Control of Nonlinear Electronic Throttle Systems
The transition from mechanical to electronic throttle control has improved the efficiency and adaptability of stoichiometric combustion engines. However, nonlinear dynamics are introduced by friction, return spring, and parameter variations, making it ...
Gustavsson, Lovisa, Karlsson, Madelene
core +1 more source
The Integrated Disturbance Estimation and Non-Singular Terminal Sliding Mode Longitudinal Motion Controller for Low-Speed Autonomous Electric Vehicles. [PDF]
Sensors (Basel)Li B +6 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Adaptive-smith predictor for controlling an automotive electronic throttle over network
The paper presents a control strategy for an automotive electronic throttle, a device used to regulate the power produced by spark-ignition engines.
Acho Zuppa, Leonardo +3 more
core
The racer's gaze: Visual strategy in high-speed sports expertise. [PDF]
J VisLappi O +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Shaping the flow characteristics of a proportional directional valve. [PDF]
Sci RepKosek M, Sliwinski P.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A comprehensive risk assessment method for Christmas tree combined with a multi source information fusion algorithm and an improved HAZOP method. [PDF]
PLoS OneWang Q, Li H, Ren G.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source