Results 61 to 70 of about 2,856 (261)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Design and control of load simulator for throttling system of large hydraulic press
The Journal of Engineering, 2018 In order to improve the precision of the extrusion speed control of the large hydraulic press and improve the quality of the extruding work piece, an experimental system was designed to simulate the throttle system of the hydraulic press.
Le Zeng +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Car-following Model of Connected Cruise Control Vehicles to Mitigate Traffic Oscillations
Promet (Zagreb), 2019 With the aim of mitigating traffic oscillations, this paper extends a car-following model for Connected Cruise Control (CCC) systems by considering electronic throttle angles of multiple cars ahead. The linear stability condition of the proposed model is
Yanyan Qin, Hao Wang, Quan Chen, Bin Ran
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Design and Simulation of Shift Schedule for Modular Automatic Transmission
Jixie chuandong, 2018 A dynamic shift schedule is designed for the prototype of hydraulic power shift automatic transmission. The steady-state schedule cannot adapt to dynamic condition,aiming at the problems including wrong shift caused by sudden change of throttle,a four ...
Wang Yanzhong +4 more
doaj
Design of electric control system for coalbed methane truck-mounted drilling rig
Gong-kuang zidonghua, 2019 Aiming at problem that traditional mechanical instrumens and hydraulic control modes cannot meet requirements of safe, accurate and efficient construction of coalbed methane truck-mounted drilling rig, an electric control system for coalbed methane truck-
ZHAO Liang
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source