Results 121 to 130 of about 187,045,675 (194)

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

Image steganography techniques for resisting statistical steganalysis attacks: A systematic literature review. [PDF]

PLoS One
Apau R, Asante M, Twum F, Ben Hayfron-Acquah J, Peasah KO.   +4 more
europepmc   +1 more source

Challenges and Limitation Analysis of an IoT-Dependent System for Deployment in Smart Healthcare Using Communication Standards Features. [PDF]

Sensors (Basel), 2023
Upadhyay S, Kumar M, Upadhyay A, Verma S, Kavita, Kaur M, Khurma RA, Castillo PA.   +7 more
europepmc   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

Advanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton, Carrillo Paola Gonzalez, Luay Almassalha, Wing Shun Li, Ruyi Gong, Nicolas Acosta, I Chae Ye, Jane Frederick, Christopher Hogg, Saira John, J. A. Gareth Williams, Rikkert J. Nap, Igal Szleifer, Vadim Backman   +13 more
wiley   +1 more source

A 4D hyperchaotic image encryption scheme using Circular Radius-Angle Transformation and bit-level permutation. [PDF]

PLoS One
Khalaf MA, Sheikh UU, Manan SSBA, Hamood SF, Najamuddin.   +4 more
europepmc   +1 more source

Deep‐Learning‐Driven High‐Fidelity In Vivo Hyperspectral Fluorescence Imaging Under Extreme Photon‐Limited Conditions

Advanced Science, EarlyView.
Highly overlapping fluorescent signals become distinguishable in photon‐limited living organisms via advanced imaging with intelligent reconstruction. The resulting in vivo hyperspectral imaging capability reveals nanoplastic uptake and circulation in live zebrafish, providing a new approach for studying complex biological and environmental processes ...
Renjian Li, Shutao Wu, Kaixiang Li, Zhenyu An, Yuwen Ben, Guiye LI, Sunil Kumar, James Mcginty, Tawfique Hasan, Songnian Fu, Meng Zhang, LingLing Chen   +11 more
wiley   +1 more source

LEACH Protocol Evolution in WSN: A Review of Energy Consumption Optimization and Security Reinforcement. [PDF]

Sensors (Basel)
Chu A, Zhang T, Wang C.
europepmc   +1 more source

Ensuring privacy and confidentiality of cloud data: A comparative analysis of diverse cryptographic solutions based on run time trend. [PDF]

PLoS One, 2023
Dawson JK, Frimpong T, Hayfron Acquah JB, Missah YM.   +3 more
europepmc   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Longitudinally engineered metasurfaces for 3D vectorial holography. [PDF]

Light Sci Appl
Tan L, Huo P, Lin P, Ren Y, Qi H, Fang L, Wang Y, Ou J, Lu Y, Xu T.   +9 more
europepmc   +1 more source