Results 61 to 70 of about 127,095 (220)
AgriFood: Journal of Agricultural Products for Food, EarlyView.GSP extends C. elegans lifespan, enhances stress resistance and reproduction, boosts antioxidant defenses (↑SOD/CAT/GSH‐Px, ↓ROS), remodels glycolysis/TCA/one‐carbon metabolism dose‐dependently, and activates SKN‐1/Nrf2 and H3K4 methylation—linking redox control to epigenetic modulation.
Boya Ouyang +7 more
wiley +1 more source
Science and Technology of Advanced Materials, 2008 The magnetic field effect (MFE) in conjunction with laser flash photolysis has been used for the study of the interaction of one of the small drug like quinone molecules, 2-methyl, 1,4-naphthoquinone, commonly known as menadione (MQ), with one of the DNA
Adity Bose, Debarati Dey and Samita Basu
doaj
Molecular Imaging, 2002 2-[ 11 C]Thymidine (TdR), a PET tracer for cellular proliferation, may be advantageous for monitoring brain tumor progression and response to therapy. We previously described and validated a five-compartment model for thymidine incorporation into DNA in ...
Joanne M. Wells +6 more
doaj +1 more source
Cardiovascular Diabetology, 2007 Background Inhibition of vascular smooth muscle cell (vSMC) proliferation by oral anti-hyperglycemic agents may have a role to play in the amelioration of vascular disease in diabetes.
de Dios Stephanie T +5 more
doaj +1 more source
Advanced NanoBiomed Research, EarlyView.Glioblastoma mortality is driven by cell invasion and therapeutic resistance. We report a cancer engineering approach to evaluate the behavior of heterogeneous cohorts of temozolomide resistant and responsive GBM cells. We show the effect of physiologically‐relevant metronomic dosing on ensemble drug response and invasion.
Victoria A. Kriuchkovskaia +5 more
wiley +1 more source
20-HETE inhibits the proliferation of vascular smooth muscle cells via transforming growth factor-β
Journal of Lipid Research, 2008 20-Hydroxyeicosatetraenoic acid (20-HETE), a cytochrome P450 arachidonic acid metabolite, has been shown to modulate the growth of vascular smooth muscle cells (VSMCs).
Chan-Jung Liang +3 more
doaj +1 more source
Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody
Animal Research and One Health, EarlyView.This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis +5 more
wiley +1 more source
Mycoplasma PneumoniaeThymidine Phosphorylase
Nucleosides, Nucleotides and Nucleic Acids, 2014 Mycoplasma pneumoniae (Mpn) is a human pathogen causing acute respiratory diseases and accounts for approximately 30% cases of community-acquired pneumonia. Co-infection with Mycoplasmas compromises the efficacy of anticancer and antiviral nucleoside analog-based drugs due to the presence of Mycoplasma thymidine phosphorylase (TP).
Wang, L. +2 more
openaire +3 more sources
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source