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Pharmacokinetic study of thymol after intravenous injection and high‐dose inhalation in mouse model [PDF]

open access: yesPharmacology Research & Perspectives, 2019
Thymol is generally recognized as a safe substance by the FDA and has been widely used in the pharmaceutical, food, and cosmetic industries. Pharmacokinetic (PK) studies of thymol have been previously conducted for oral administration, but there has been
Kevin Xie   +3 more
doaj   +3 more sources

Fabrication of Caseinate Stabilized Thymol Nanosuspensions via the pH-Driven Method: Enhancement in Water Solubility of Thymol

open access: yesFoods, 2021
Thymol has been applied as a spice and antibacterial agent in commercial products. However, the utilization of thymol in the food and pharmaceutical field has recently been limited by its poor water solubility and stability.
Wei Zhou, Ruyi Li, Shengfeng Peng
exaly   +3 more sources

Diet Acceptance and Utilization Responses to Increasing Doses of Thymol in Beef Steers Consuming Forage [PDF]

open access: yesAnimals
Thymol is an antimicrobial terpene with potential as a feed additive for cattle; however, in vivo data describing the response of forage-fed beef cattle to the increasing provision of thymol is limited.
Emma P. Fukuda   +3 more
doaj   +2 more sources

Growth Inhibition, Mortality Induction, Adverse Impacts of Development, and Underlying Molecular Mechanisms of Thymol Against Spodoptera frugiperda [PDF]

open access: yesInsects
The global migratory pest, Spodoptera frugiperda, has garnered widespread attention due to the serious damage it inflicts on agricultural productivity, particularly in maize.
Huiyin Hu   +7 more
doaj   +2 more sources

The Fungicidal Activity of Thymol against Fusarium graminearum via Inducing Lipid Peroxidation and Disrupting Ergosterol Biosynthesis

open access: yesMolecules, 2016
Thymol is a natural plant-derived compound that has been widely used in pharmaceutical and food preservation applications. However, the antifungal mechanism for thymol against phytopathogens remains unclear.
Wei Zhou, Jian Chen
exaly   +3 more sources

Bioavailability of Thymol Incorporated into Gastro-Resistant Self-Emulsifying Pellets in Rabbits [PDF]

open access: yesAnimals
Thymol gastro-resistant self-emulsifying pellets were used to achieve thymol targeted release on the side of the intestine with the most intensive absorption to enhance its oral bioavailability.
Radoslava Kristofova   +8 more
doaj   +2 more sources

Antimicrobial activity of nanoformulations of carvacrol and thymol: New trend and applications

open access: yesOpenNano, 2023
Thymol and carvacrol are aromatic compounds derived from plants that exhibit considerable broad-spectrum antimicrobial effects. They have also shown extensive biological effects, including antispasmodic, anti-inflammatory, and anti-carcinogenic ...
Aida Hajibonabi   +5 more
exaly   +3 more sources

Fabrication and Characterization of Gelatin/Zein/Thymol Nanofibers by Electro-blown Spinning [PDF]

open access: yesShipin Kexue, 2023
In this study, gelatin/zein/thymol nanofibers were fabricated by electro-blown spinning technique, and its microscopic morphology and diameter distribution were characterized by scanning electron microscopy (SEM).
LIU Songqi, XIANG Hui, WU Jingjing, Maierhaba·TAXIPALATI, AN Jianhui, ZHOU Zhi, DENG Lingli
doaj   +1 more source

Encapsulation of Thymol in Gelatin Methacryloyl (GelMa)-Based Nanoniosome Enables Enhanced Antibiofilm Activity and Wound Healing

open access: yesPharmaceutics, 2023
Non-healing wounds impose huge cost on patients, healthcare, and society, which are further fortified by biofilm formation and antimicrobial resistance (AMR) problems. Here, Thymol, an herbal antimicrobial agent, is utilized to combat AMR.
Maryam Moghtaderi   +6 more
doaj   +1 more source

Thymol Nanopolymer Synthesis and Its Effects on Morphine Withdrawal Syndrome in Comparison With Clonidine in Rats

open access: yesFrontiers in Behavioral Neuroscience, 2022
The drug delivery system is valuable in the treatment of the disease. A nanopolymer as a thymol and Thymbra spicata release system was synthesized and its effects on morphine withdrawal syndrome in comparison with clonidine in rats were studied.
Ardeshir Moayeri   +6 more
doaj   +1 more source

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