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Thyroglobulin and Thyroglobulin Antibodies
2006Thyroglobulin, an approximately 670-kDa glycopeptide, is the major protein product of thyroid follicular cells; its rate of synthesis is increased by thyrotropin (TSH). After synthesis, it is modified by the attachment of iodine to selected tyrosine residues, which undergo rearrangement to form iodothyronines, particularly thyroxine (T4) and, to a ...
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Thyroglobulin-anti-thyroglobulin immune complex glomerulonephritis complicating radioiodine therapy
Clinical Immunology and Immunopathology, 1978Abstract A case of glomerulonephritis, apparently secondary to documented deposition of thyroglobulin-anti-thyroglobulin immune complexes, is reported. A 26-year-old man developed acute glomerulonephritis 10 days after administration of 131I for treatment of thyrotoxicosis.
D W, Ploth +4 more
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Thyroglobulin and anti-thyroglobulin assays in thyroid cancer monitoring
Clinical Biochemistry, 2009To compare four methods for thyroglobulin (Tg) quantitation and three methods for detection and quantitation of thyroglobulin antibodies (Tg-Ab). We also wanted to explore the premise that thyroglobulin antibodies, as determined by commercially available assays, interfere with thyroglobulin assays in a predictable way.Split sample method comparisons ...
John, Krahn, Tom, Dembinski
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Phosphorylation of 19S Thyroglobulin
1988Thyroglobulin (TG), one of the largest known eukaryotic proteins (Mr 660.000, sedimentation coefficient 19S), plays a central role in thyroid hormonogenesis. TG presents several characteristics of special interest: (i) it represents the major biosynthetic product of thyroid follicular cell1; (ii) under denaturing conditions it can be dissociated into ...
Tassi V. +3 more
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Thyroglobulin: A Clinical Review
Endocrine Practice, 1995The introduction of the new assays for thyroglobulin (Tg) with a sensitivity of 1 to 3 mg/L has made it unnecessary to terminate thyroxine suppression therapy to determine Tg level. Thyroid-stimulating hormone should always be assessed in conjunction with the Tg to ensure that it is not high; as long as it is suppressed to normal, subnormal suppression
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Thyroglobulin measurement in the management of patients with differentiated thyroid cancer
Critical reviews in clinical laboratory sciences, 2018A. Algeciras-Schimnich
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Measurement of thyroglobulin, calcitonin, and PTH in FNA washout fluids
Clinical Chemistry and Laboratory Medicine, 2017P. Trimboli +3 more
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