Results 151 to 160 of about 825,057 (283)

NKX2‐1 Downstream Regulatory Structural Variants Explain a Substantial Proportion of Molecular Diagnoses in Patients With Benign Hereditary Chorea

open access: yesMovement Disorders, EarlyView.
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard   +33 more
wiley   +1 more source

Thyroid stimulating hormone (TSH): does it live up to its promises in the andrology laboratory? [PDF]

open access: yesBasic Clin Androl
Alizadeh Moghadam Masouleh A   +6 more
europepmc   +1 more source

Incretin‐Based Therapies: A Testable Hypothesis Linking Incretin Signaling, Mitochondrial Redox, and OXPHOS Efficiency

open access: yesObesity, EarlyView.
ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee   +2 more
wiley   +1 more source

2025 American Thyroid Association Management Guidelines for Adult Patients With Differentiated Thyroid Cancer: What's New for Surgeons?

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract The American Thyroid Association (ATA) has published an update to the 2015 management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer (DTC). This updated version focuses solely on the management of differentiated thyroid cancer, offering a comprehensive set of guidelines for all stakeholders in the care of ...
Chau Nguyen   +2 more
wiley   +1 more source

The Diagnostic Performance of Afirma Genomic Sequencing Classifier in Black and Hispanic Patients With Indeterminate Thyroid Nodules

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective About 20% of thyroid nodules detected on ultrasound are cytologically indeterminate (Bethesda categories III and IV), but the rate of malignancy of these nodules is less than 36%. The ability of Afirma Genomic Sequencing Classifier (GSC) to further risk‐stratify indeterminate thyroid nodules among Black and Hispanic patients is ...
Peter J. Attia   +5 more
wiley   +1 more source

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