Results 11 to 20 of about 454,057 (403)

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

Nature Communications, 2020
Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis at 22.4 million genetic markers in up to 119,715 individuals and identify 74
Wei Zhou, B. Brumpton, O. Kabil, J. Gudmundsson, G. Thorleifsson, Josh Weinstock, M. Zawistowski, J. Nielsen, L. Chaker, M. Medici, A. Teumer, S. Naitza, S. Sanna, Ulla T. Schultheiss, A. Cappola, J. Karjalainen, M. Kurki, M. Oneka, P. Taylor, L. Fritsche, S. Graham, B. Wolford, William Overton, Humaira Rasheed, E. Haug, M. Gabrielsen, A. Skogholt, I. Surakka, G. Davey Smith, Anita Pandit, Tanmoy Roychowdhury, W. Hornsby, J. Jónasson, L. Senter, S. Liyanarachchi, M. Ringel, Li Xu, L. Kiemeney, Huiling He, R. Netea-Maier, J. Mayordomo, T. Plantinga, J. Hrafnkelsson, H. Hjartarson, E. Sturgis, A. Palotie, M. Daly, Cintia E. Citterio, P. Arvan, C. Brummett, M. Boehnke, A. de la Chapelle, K. Stefánsson, K. Hveem, C. Willer, B. Åsvold   +55 more
semanticscholar   +1 more source

Reference Interval of Thyroid Stimulating Hormone and free Tetra-iodothyronine in Healthy Pregnant Women of Quetta, Baluchistan

Pakistan Armed Forces Medical Journal, 2022
Objective: To establish the reference intervals of thyroid stimulating hormone and free Tetraiodothyronine in healthy pregnant women of Quetta, Baluchistan. Study Design: Cross-sectional study.
Azadi Khan, Naveed Asif, Razaullah ., Taimoor Ashraf Khan, Asma Khan, Saima Shakil Malik   +5 more
doaj   +1 more source

Changes in Clinical Activity, Serum Autoantibody Levels, and Chorioretinal Vessels After Systemic Glucocorticoid Therapy in Thyroid Eye Disease

Ophthalmology and Therapy, 2023
Introduction The aim of this study was to investigate changes in the Clinical Activity Score, serum thyroid-stimulating hormone receptor antibody and thyroid-stimulating immunoglobulin levels, chorioretinal blood vessels, and extraocular muscle thickness
Jaekyoung Lee, Dong Cheol Lee
doaj   +1 more source

The Molecular Function and Clinical Role of Thyroid Stimulating Hormone Receptor in Cancer Cells

Cells, 2020
The thyroid stimulating hormone (TSH) and its cognate receptor (TSHR) are of crucial importance for thyrocytes to proliferate and exert their functions. Although TSHR is predominantly expressed in thyrocytes, several studies have revealed that functional
Yu-De Chu, C. Yeh
semanticscholar   +1 more source

Alternating Hypothyroidism and Hyperthyroidism in an Adolescent Boy – Do We Always Understand What Drives the Switch?

Acta Clinica Croatica, 2023
Alternating hypothyroidism and hyperthyroidism is a rare phenomenon, especially among pediatric patients. It is usually related to simultaneous, unbalanced presence of stimulating and blocking thyroid stimulating hormone receptor antibodies (TRAbs ...
Lavinia La Grasta Sabolić, Marija Požgaj Šepec, Gordana Stipančić   +2 more
doaj   +1 more source

Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]

, 2013
The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
A Mansukhani, AK Coussens, BD Stamper, BK Huang, BU Ang, C Owen, C Yao, CB Harvey, CH Shackleton, CW Li, D Gomez, D Johnson, DC Robinson, DP Rice, DT Gault, G Radetti, G Ramajayam, GA Brent, GM Morriss-Kay, GR Williams, H Kohara, H Miraoui, HJ Kim, J Connerney, J Esparza, J Zumbrunn, JA Greenwald, Jack C. Yu, James J. Cray, JH Bassett, JH Oh, JL Penfold, JM Britto, JQ Feng, JS Morey, K Kasono, KA Kapp-Simon, Kameron Khaksarfard, KM Lee, M Bodo, M Menking, M Segni, MH Sheng, MM Cohen Jr, Mohammed Elsalanty, PJ Marie, R Rice, S Akita, S Wadhwa, S Weiss, SA Boyadjiev, SA Rasmussen, Seth M. Weinberg, W Arlt, W Riggs Jr, WM Chadduck, Xing-Ming Shi, Y Xiong, Z von Marschall   +58 more
core   +8 more sources

Thyroid function tests [PDF]

, 2011
Thyroid disorders can be difficult to detect clinically, but thyroid function tests can assist in making a diagnosis. Measuring thyroid stimulating hormone is the first step. If it is abnormal, free thyroxine should be measured. A raised concentration of
Mortimer, Robin H.
core   +1 more source

The prognostic value of thyroid-stimulating immunoglobulin in the management of Graves’ disease

Therapeutic Advances in Endocrinology and Metabolism, 2021
Background: The bioassay of thyroid-stimulating immunoglobulin was reported to have a similar performance to the commonly used thyroid-stimulating hormone binding inhibition assay, also known as thyroid receptor antibody assay. The normal reference range
Yulin Zhou, Mengxi Zhou, Yicheng Qi, Weiqing Wang, Xinxin Chen, Shu Wang   +5 more
doaj   +1 more source

Maternal thyroid function and child educational attainment: prospective cohort study [PDF]

, 2018
Objective: To determine if first trimester maternal thyroid dysfunction is a critical determinant of child scholastic performance and overall educational attainment. Design: Prospective cohort study.
Haig, Caroline, Lawlor, Debbie A., Lindsay, Robert S., McConnachie, Alex, Nelson, Scott M., Ring, Susan M., Sattar, Naveed, Smith, George D.   +7 more
core   +3 more sources

A negative correlation of thyroid stimulating hormone with anti_mullerian hormone and with luteinizing hormone in polycystic ovary syndrome and/or hypothyroid women

Middle East Fertility Society Journal, 2018
Background: Using anti_mullerian hormone (AMH) for Polycystic Ovary Syndrome diagnosis is not always constant. Thyroid dysfunction may effect on AMH levels.
Samal Hakeem Kareem AL-Jaff
doaj   +1 more source