Results 211 to 220 of about 825,057 (283)

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Coexistence of Resistance to Thyroid Hormone and a Thyroid Stimulating Hormone-Secreting Pituitary Adenoma. [PDF]

AACE Endocrinol Diabetes
Koo TH, Gharib H.
europepmc   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

An Enhanced Electrochemiluminescence Immunoassay Platform via Optimized Magnetic Bead Uniformity for Reliable Thyroid-Stimulating Hormone Monitoring. [PDF]

Bioengineering (Basel)
Lei H, Huang X, Cao X, Tang Y, Ge Y.
europepmc   +1 more source

Tumor‐Derived Exosomal piR‐hsa‐28212 Promotes Lymphatic Metastasis in Breast Cancer

Cancer Science, EarlyView.
Breast cancer–derived exosomal piR‐hsa‐28212 promotes lymphangiogenesis and lymph node metastasis by activating VEGFC/VEGFR3 signaling. It stabilizes TBX1 mRNA in lymphatic endothelial cells and METTL3 protein in tumor cells, enhancing VEGFR3 expression and VEGFC secretion.
Yafen Wang, Tianli Zhang, Xue Kong, Yao Tong, Yanru Li, Xiangjun Dong, Chuanxin Wang, Juan Li   +7 more
wiley   +1 more source

Performance evaluation and reference interval establishment of Abbott Alinity thyroid-stimulating hormone receptor antibody (TRAb) assay for diagnosing Graves' disease. [PDF]

PLoS One
Xue H, Li B, Wang X, Zhao J, Yan Y, Lao J, Ji L, Xia Y.   +7 more
europepmc   +1 more source

What Endocrinologists Should Know About Iodine: Population Deficiency, Individual Excess and Misinformation in the United Kingdom

Clinical Endocrinology, EarlyView.
ABSTRACT Iodine deficiency, once considered eliminated in the United Kingdom, has re‐emerged, particularly among women of reproductive age, in whom requirements are increased during pregnancy and lactation. The declining consumption of dairy and white fish, the emerging use of unfortified plant‐based milk alternatives, and the absence of a national ...
Peter N. Taylor, Malcolm Prentice, Sarah Bath, Emilie Combet, Nadia Schoenmakers, Vicki E. Smith, Fraser W. Gibb, Nicola Zammitt, Onyebuchi Okosieme, Kristien Boelaert, John Lazarus, Mark Vanderpump   +11 more
wiley   +1 more source

Expression, immunogenicity and clinical significance analysis of thyroid‑stimulating hormone receptor fusion proteins. [PDF]

Mol Med Rep
Chen X, Chen H.
europepmc   +1 more source

Subacute Thyroiditis in Denmark: A Nationwide Study of 1763 Cases

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Subacute thyroiditis (SAT) is a differential diagnosis in the clinical care of hypo‐ and hyperthyroid patients, but large‐scale population data on the incidence, patient characteristics, and outcome are limited. Thus, the aim was to determine the incidence of SAT in the Danish population and to characterise patient demographics and ...
Marco Juul Thomsen, Niels Henrik Bruun, Nanna Maria Uldall Torp, Jesper Karmisholt, Stig Andersen, Stine Linding Andersen   +5 more
wiley   +1 more source

Anti-Thyroid Peroxidase Antibodies and Thyroid-Stimulating Hormone for Risk Stratification of Subclinical Thyroid Dysfunction in Patients With Type 2 Diabetes Mellitus. [PDF]

AACE Endocrinol Diabetes
Mohammedsaeed W, Alfahl S, Aljohani R, Alamri A, Almutairi S, Almutairi M.   +5 more
europepmc   +1 more source