Results 91 to 100 of about 74,876 (285)

Genetic Alterations in the SERPIN Gene Family as Predictors of Immune Checkpoint Therapy Efficacy in Melanoma and Non‐Small Cell Lung Cancer

open access: yesMedicine Advances, EarlyView.
This study demonstrated a clear association between serine protease inhibitor (SERPIN) gene alterations and clinical outcomes in patients with melanoma and non‐small cell lung cancer receiving immune checkpoint inhibitor therapy across five cohorts.
Jieqiong Li   +5 more
wiley   +1 more source

miR-191 downregulation plays a role in thyroid follicular tumors through CDK6 targeting

open access: yes, 2010
miR-191 expression is frequently altered in several neoplasias, being upregulated in some, such as pancreatic, colon, lung and prostate carinomas, and downregulated in others, such as severe medulloblastomas and melanomas.
Colamaio, Marianna
core  

The Role of Thyroidectomy in the Management of Thyroglossal Duct Carcinoma: A Systematic Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective The extent of surgical management of thyroglossal duct‐associated differentiated thyroid carcinoma remains controversial. This study aims to evaluate the role of total thyroidectomy in patients with thyroglossal duct‐associated differentiated thyroid carcinoma and provide insights to support individualized, evidence‐based care.
Hidde H. IJtsma   +6 more
wiley   +1 more source

“The potential role of CXCR4 and SDF-1 as indicators of tumor aggressiviness in patients with conventional papillary thyroid carcinoma”

open access: yes, 2008
Background: Functional chemokine receptors are expressed in many malignant tumors, including papillary thyroid carcinoma (PTC). These receptors promote tumor growth and metastasis in response to endogenous chemokines.
Pagano, Loredana
core  

Avaliação ultrassonográfica das metástases linfonodais para compartimento central em pacientes com carcinoma bem diferenciado da tireóide [PDF]

open access: yes, 2009
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Manoel, Evandro Maccarini
core  

Postnatal Expression of BRAFV600E Does Not Induce Thyroid Cancer in Mouse Models of Thyroid Papillary Carcinoma

open access: yes, 2013
The mutant BRAF (BRAFV600E) is the most common genetic alteration in papillary thyroid carcinomas (PTCs). The oncogenicity of this mutation has been shown by some genetically engineered mouse models.
Nakashima, Masahiro   +10 more
core   +1 more source

Clinical Applications of Multimodal Artificial Intelligence in Otolaryngology: A State‐of‐the‐Art Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Artificial intelligence (AI) has advanced to simultaneously process visual, auditory, and textual inputs, providing users with “multimodal” AI. Given the clinical integration potential of these tools, otolaryngologists must stay informed. This study reviews current literature on applications of multimodal AI in otolaryngology.
Ying Jie Li   +5 more
wiley   +1 more source

Biological function of Cl 2 gene and it’s role in thyroid cancer

open access: yes, 2011
Here I report data to support a tumor suppressor role of the Cl 2 gene. Indeed, I detected a drastic reduction, of Cl 2 gene expression in almost all thyroid carcinomas analyzed, with respect to normal thyroid, with the lowest expression levels observed ...
Ferraro, Angelo
core  

Results of Surgical Treatment of Papillary Thyroid Cancer

open access: yesКлиническая и экспериментальная тиреоидология, 2014
Thyroid papillary cancer, one of the most frequent malignant tumors, aroused growing interest during last years due to continuous increase in number of such patients.

doaj   +1 more source

The Molecular Heterogeneity of NRAS Variants in Thyroid Nodules

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective NRAS variants are the most common mutations in thyroid nodules with (B)ethesda III/IV cytology. This study aims to characterize co‐occurring variants, molecular signatures, and hallmarks of cancer pathways in nodules with NRAS variants. Study Design Retrospective database analysis.
Emma De Ravin   +5 more
wiley   +1 more source

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