Results 91 to 100 of about 3,138,389 (246)

Liposomal siRNA Delivery in Papillary Thyroid Carcinoma Cells

, 2022
The discovery of RNA interference (RNAi) has opened a new strategy in cancer therapy, especially by silencing target genes. Pharmacologically it can be achieved by introducing of small (19–21 base pairs) dsRNA molecules known as small interfering RNA ...
Islam, F, Lam, AK, Zhou, Y
core   +1 more source

Bisphenol A Induces DNA Damage and Differential Cytotoxicity in Thyroid Cells: High‐Dose Effects Challenge Regulatory Thresholds

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, has been implicated in carcinogenesis; however, its effects on thyroid cells remain unclear. This study investigated BPA‐induced cytotoxicity and genotoxicity in thyroid cell lines, including normal follicular (Nthy‐ori 3‐1), papillary carcinoma (TPC‐1 and BCPAP) and anaplastic
Izabela Fernanda Dal' Bó, Natássia Elena Bufalo, Valdemar Máximo, Laura Sterian Ward   +3 more
wiley   +1 more source

The mechanism of fibronectin 1 promoting papillary thyroid cancer progression by regulating anoikis resistance

Scientific Reports
Background: Papillary thyroid cancer is a common head and neck malignancy with a globally rising incidence. While most patients attain favorable prognosis following standard treatment, a subset develops recurrence and metastasis—two key factors that ...
Shengcan Zhang, Xue Gu, Xinyu Zhai, Hanzhao Huang, Renjie Zhang, Hui Ye   +5 more
doaj   +1 more source

Mönckeberg sclerosis in patients with thyroid papillary carcinoma

Endocrine Oncology
Background: Mönckeberg sclerosis is a form of calcification of the tunica media of small and medium size arteries. It occurs more often in the peripheral arteries of the lower limbs and it has been associated with diabetes and renal disease.
Vasiliki Venetsanaki, Eleana Zisimopoulou, Chrysanthi Zouli, Maria Boudina, Konstantinos Gkiouras, Persefoni Xirou, Aimilia Fotiadou, Mariana Stamati, Elpiniki Argyropoulou, Alexandra Chrisoulidou   +9 more
doaj   +1 more source

Improving the Accuracy of Papillary Thyroid Cancer Pathological Evaluation With Digital PCR Detection of the BRAF V600E Mutation

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a highly sensitive and specific digital PCR assay for BRAF V600E mutation detection in papillary thyroid cancer (PTC). The increased sensitivity of BRAF mutation detection directly led to more accurate pathological diagnosis of PTC and in turn improved clinical care in patients with limited sample availability or in samples with ...
Na Yu, Kai Zhang, Ying Jiang, Liang Zheng, Xiu He, Qinglin He, Meng Dai, Tianhua Hu, Dongfang Tang, Jingjing Jin, Xin Huang, Li Xiao   +11 more
wiley   +1 more source

Adult women with papillary thyroid cancer

Romanian Medical Journal, 2019
Differentiated thyroid cancer of papillary type have an increasing incidence on women of reproductive age but also in menopause, possible related to new triggers that act as endocrine disruptors which are more or less described until this moment or possible related to the increased accessibility to thyroid ultrasound.
Adina Ghemigian, Mara Carsote, Ana Valea, Ancuta Augustina Gheorghisan-Galateanu, Rucsandra Danciulescu-Miulescu, Diana Loreta Paun   +5 more
openaire   +2 more sources

Thyroid Papillary Microcarcinoma: Diagnostic and Treatment Approaches [PDF]

, 2014
The commonly occurring differentiated thyroid cancer is microcarcinoma, which is diagnosed by high-resolution ultrasound and fine-needle aspiration cytology.
Evren Erkul
core   +1 more source

Macroscopic Examination of Surgical Specimen of Papillary Thyroid Carcinoma

, 2022
Standardized pathology reporting of thyroid cancer is important for quality clinical management, research as well as education purposes. International Collaboration on Cancer Reporting (ICCR) has produced a Dataset for reporting carcinoma of thyroid.
Lam, AK
core   +1 more source

DNA Extracted From Aged Formalin‐Fixed Paraffin‐Embedded Specimens of Patients With Papillary Thyroid Carcinomas Can Be Used for Whole Exome Sequencing

Journal of Clinical Laboratory Analysis, EarlyView.
We aimed to assess the quality of DNA extracted from long‐term stored FFPE specimens of patients with papillary thyroid carcinoma from three hospitals in Hiroshima and their applicability to whole exome sequencing. FFPE samples preserved for up to 55 years may be amenable to sequencing with increased read depth.
Kousuke Tanimoto, Tomonori Hayashi, Hidewaki Nakagawa, Kazuhiro Maejima, Koji Arihiro, Megumu Fujihara, Takashi Nishisaka, Masahiro Ito, Masahiro Nakashima, Naohiro Kato, Zhenqiu Liu, Misa Imaizumi, Alina Brenner, Stephen J. Chanock, Osamu Tanabe, Kotaro Ozasa   +15 more
wiley   +1 more source

Significance of TROP-2 and P63 Expression in Diagnosis of Papillary Thyroid Lesions: An immunohistopathological Study [PDF]

Zagazig University Medical Journal, 2018
Background: Thyroid cancer is the most common endocrine malignancy, accounting for 2.1% of all cases of cancer worldwide. About 77% of these cases occurring in women[1]. Approximately 90% of all thyroid cancers are differentiated; meaning that they arise
doaj   +1 more source