Results 41 to 50 of about 3,138,389 (246)

Evaluation of Proinflammatory Cytokine and Neopterin Levels in Women with Papillary Thyroid Carcinoma

The International Journal of Biological Markers, 2016
Introduction Papillary thyroid cancer is a disease that has been associated with chronic inflammation. The purpose of this study is to measure the production of the proinflammatory cytokines IL-1β, IL-6 and IL-8 and neopterin, which is a novel biomarker ...
Kemal Beksac MD, Cigdem Sonmez, Bahadir Cetin, Gorkem Kismali, Tevhide Sel, Yildirim Tuncer, Funda Kosova   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

087. Relationship Between Neutrophil-Lymphocyte Ratio and Serum Thyroid Stimulating Hormone Preoperative Thyroidectomy as Predictors of Papillary Thyroid Cancer

JBN (Jurnal Bedah Nasional)
Background: Thyroid cancer is the most common endocrine malignancy. The incidence of papillary thyroid cancer has been increasing. Early diagnosis and management are crucial for thyroid cancer.
William Stevenson, Nico Lumintang, Sherly Tandililing, Windy Mariane Virenia Wariki   +3 more
doaj   +1 more source

Concepts of Pathological Staging and Prognosis in Papillary Thyroid Carcinoma

, 2022
American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (AJCC/UICC) staging and American Thyroid Association (ATA) risk predication system are the best predicators of mortality and cancer recurrence, respectively, in patients ...
Lam, AK
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Overdiagnosis of Papillary Thyroid Cancer

JAMA Network Open
Importance The magnitude of thyroid cancer overdiagnosis in the US, accounting for the true increase in underlying disease, has not been quantified.
Francis, David O., Davies, Louise, Zhang, Yichi, Arroyo, Natalia, Fernandes-Taylor, Sara, Nordby, Peter, Cher, Ben A. Y., Venkatesh, Manasa, Aiello Bowles, Erin J., Alagoz, Oguzhan   +9 more
openaire   +3 more sources

Hashimoto's Thyroiditis and Papillary Thyroid Cancer [PDF]

Journal of Korean Thyroid Association, 2014
The association of Hashimoto’s thyroiditis (HT) with papillary thyroid cancer (PTC) has been still under debate. Some suggest that these two are positively correlated, whereas other studies report no relationship. We performed a systematic literature review of original studies to investigate the correlation between HT and PTC. The existing data provide
openaire   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes

Frontiers in Public Health
IntroductionThe growing popularity of active surveillance for papillary thyroid cancer and the COVID-19 pandemic have increased surgery delay, further necessitating a reassessment of the link between surgery delay and survival outcomes for papillary ...
Kun Zhang, Xinyi Wang, Jianyong Lei, Anping Su, Tao Wei, Zhihui Li, Ya-Wen Chen, Ya-Wen Chen, Ya-Wen Chen, Ya-Wen Chen, Ya-Wen Chen   +10 more
doaj   +1 more source

MiR-886-3p regulates cell proliferation and migration, and is dysregulated in familial non-medullary thyroid cancer. [PDF]

PLoS ONE, 2011
The molecular basis and characteristics of familial non-medullary thyroid cancer are poorly understood. In this study, we performed microRNA (miRNA) profiling of familial and sporadic papillary thyroid cancer tumor samples.Genome wide miRNA profiling of ...
Yin Xiong, Lisa Zhang, Alisha K Holloway, Xiaolin Wu, Ling Su, Electron Kebebew   +5 more
doaj   +1 more source