Results 131 to 140 of about 253,005 (263)

Tumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis

iLABMED, EarlyView.
We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang, Xueying Zhang, Wen Deng, Fangning Gao, Shujia Peng, Guoqiang Bao, Lijuan Yuan   +6 more
wiley   +1 more source

Review of Genomic Drivers of Thyroid Cancer and Their Clinical Implications. [PDF]

Genes (Basel)
Mohammed S, Mettman D, Breier AH, Patel V, Garcia-Touza M.   +4 more
europepmc   +1 more source

Thyroid cancer incidence [PDF]

Nature, 1992
E, Ron, J, Lubin, A B, Schneider
openaire   +2 more sources

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Differences in the aggressiveness of familial versus sporadic non-medullary thyroid cancer: An unresolved controversy. [PDF]

Arch Endocrinol Metab
Miasaki FY, Cavalcanti TCS, Graf H, Kimura ET, Kopp PA, Carvalho GA.   +5 more
europepmc   +1 more source

Comprehensive assessment of unfolded protein response and its association with tumor progression in pan‐cancer

iMetaOmics, EarlyView.
Schematic of the study design. In this study, we developed a comprehensive unfolded protein response (UPR) gene signature and applied it to systematically characterize the UPR landscape across multiple cancer types. By integrating bulk and single‐cell transcriptomic data, we revealed substantial inter‐ and intra‐tumoral heterogeneity in UPR activity ...
Xinyu Yang, Faming Zhao, Jing Yang, Xinran Xia, Liwei Chen, Peng Zeng, Liang Chen, Yanxia Hu, Xia Sheng   +8 more
wiley   +1 more source

Pembrolizumab in recurrent or metastatic medullary thyroid cancer. [PDF]

Oncologist
Del Rivero J, Donahue RN, Marte JL, Gramza A, Cordes L, Karzai F, Abel ML, Schlom J, Gulley JL, Madan RA.   +9 more
europepmc   +1 more source

Microbial metabolites in tumor epigenetic regulation

iMeta, EarlyView.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Overdiagnosis of Papillary Thyroid Cancer.

JAMA Netw Open
Francis DO, Davies L, Zhang Y, Arroyo N, Fernandes-Taylor S, Nordby P, Cher BAY, Venkatesh M, Aiello Bowles EJ, Alagoz O.   +9 more
europepmc   +1 more source

Endocrine-disrupting chemicals and thyroid cancer. [PDF]

Turk J Med Sci
Baş Aksu Ö, Şahin M.
europepmc   +1 more source