Results 251 to 260 of about 254,610 (274)

Histologically verified penile lichen sclerosus—Incidence in Denmark over 26 years and long‐term risk of penile and non‐penile cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk   +5 more
wiley   +1 more source

Recent Advancements in Microfluidic Biosensors for Clinical Applications

open access: yesiLABMED, EarlyView.
The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid and accurate detection of complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, and treatment management.
Haiyan Wang, Wenjuan Wu
wiley   +1 more source

Novel machine‐learning bioinformatics reveal distinct metabolic alterations for enhanced colorectal cancer diagnosis and monitoring

open access: yesiMetaOmics, EarlyView.
The PANDA pipeline for colorectal cancer (CRC) analysis integrates metabolomic data from LC‐MS with machine learning techniques to classify CRC stages and predict biomarkers. Initially, the raw metabolomic data is processed using partial least squares discriminant analysis (PLS‐DA) to reduce dimensionality and highlight key features.
Rui Xu   +8 more
wiley   +1 more source

Linking preclinical models to clinical realities: VEGF/VEGFR inhibitors and thrombotic microangiopathy in cancer therapy

open access: yesiMetaOmics, EarlyView.
This study investigates the risk of thrombotic microangiopathy (TMA) induced by vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor (VEGFR) inhibitors in cancer therapy. Using data from the FDA Adverse Event Reporting System (FAERS), the WHO Global Database for Adverse Drug Reactions (Vigibase), and The Cancer ...
Aimin Jiang   +7 more
wiley   +1 more source

Tenascin-C Potentiates Wnt Signaling in Thyroid Cancer.

open access: yesEndocrinology
Hartmann HA   +25 more
europepmc   +1 more source

The influence of microbiome‐derived amino acids metabolites in shaping the glioma immunosuppressive microenvironment

open access: yesInterdisciplinary Medicine, EarlyView.
Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma   +10 more
wiley   +1 more source

NF-κB in Thyroid Cancer: An Update. [PDF]

open access: yesInt J Mol Sci
Crescenzi E, Leonardi A, Pacifico F.
europepmc   +1 more source

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