Results 311 to 320 of about 5,282,014 (364)

SLPI as a dedifferentiation biomarker in BRAFV600E-mutant papillary thyroid cancer. [PDF]

Endocr Connect
Luo W, Ji X, Tan XY, Li YT, Zhang ZQ, Zeng CM.   +5 more
europepmc   +1 more source

Impact of the updated tnm staging criteria on prediction of persistent disease in a thyroid cancer cohort

, 2018
C Nava, André Borsatto Zanella, Rafael Selbach Scheffel, Ana Luiza Maia, José Miguel Dora   +4 more
openalex   +1 more source

TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer

iMetaOmics, EarlyView.
This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin, Kunhua Hu, Hongyan Sun, Xiaoqiong Bao, Lin Tang, Wei Liu, Zhixiang Zuo, Zhihang Chen   +7 more
wiley   +1 more source

Molecular Mechanisms of Thyroid Hormone Signaling in Thyroid Cancer: Oncogenesis, Progression, and Therapeutic Implications. [PDF]

Biomedicines
Zhou C, Liu W, Zheng J, Wu Q, Ai Z.
europepmc   +1 more source

Homoharringtonine suppresses acute myeloid leukemia progression by orchestrating EWSR1 phase separation in an m6A‐YTHDF2‐dependent mechanism

iMeta, EarlyView.
Homoharringtonine (HHT), a clinically approved anti‐leukemic drug, directly binds the RNA‐binding protein EWSR1. HHT induces an allosteric conformational switch in the RNA recognition motif of EWSR1, driving self‐association and liquid–liquid phase separation (LLPS). The resulting condensates act as regulatory hubs that sequester the m6A reader YTHDF2,
Ting‐Ting Liu, Li‐Ting Chen, Xu‐Ying Pei, Shao‐Nan Hu, Fang‐Fang Zhuo, Ze‐Kun Chen, Yang Liu, Jing‐Kang Wang, Ji‐Chao Zhang, Qi Cao, Ling Li, Jing Wang, Tian‐Tian Wei, Bo Han, Peng‐Fei Tu, Xiang‐Yu Zhao, Ruidong Xue, Ke‐Wu Zeng   +17 more
wiley   +1 more source

Thyroid Cancer in a Psoriatic Patient Treated With Secukinumab: A Case Report and Literature Review. [PDF]

Cureus
Alyousef A, Attia H, Alsulaili M, Aldhafiri S, Sakr H.   +4 more
europepmc   +1 more source

Mitochondrial fission protein 1 in the regulation of mitochondrial quality control: A cancer perspective

Interdisciplinary Medicine, EarlyView.
Background: Mitochondrial fission protein (FIS1), affecting energy metabolism and homeostasis, is crucial for mitochondrial quality control (MQC) and tumor progression. Key Points: It varies in expression across TME, influencing tumor progression.
Chao Wei, Xiaoling Yuan, Xiaoli Liu, Jia Feng, Miao Song, Xuexue Liu, Jiahong Zhou, Jinbo Liu   +7 more
wiley   +1 more source

New trend in molecular diagnostics: Insights from the tumor microenvironment

Interdisciplinary Medicine, EarlyView.
The graphical abstract outline the key elements in TME‐based molecular diagnostics, including biomarker exploration, diagnostic methods, and diagnostic models. Source: Created with BioRender.com. Abstract Molecular diagnosis has revolutionized cancer precision medicine.
Baiyuan Fan, Jiahui Zhang, Chong Li, Xu Zhang   +3 more
wiley   +1 more source

Epigenetic Remodeling in Thyroid Cancer: New Dimensions of Targeted Therapy Through lncRNA Modulation. [PDF]

Curr Issues Mol Biol
Albulescu A, Fudulu A, Mihaila MA, Iancu I, Plesa A, Bostan M, Botezatu A, Brasoveanu LI, Hotnog CM.   +8 more
europepmc   +1 more source