Results 61 to 70 of about 5,153,703 (360)

Role of elective neck dissection in cT2N0 maxillary sinus squamous cell carcinoma

Scientific Reports
Our objective was to examine the impact of elective neck dissection (END) on the prognosis of patients with cT2N0 maxillary sinus squamous cell carcinoma (MS-SCC) and to determine factors that predict the occurrence of occult metastasis in this patient ...
Jingjing Wang, Qigen Fang, Xu Zhang, Liyuan Dai, Ruihua Luo   +4 more
doaj   +1 more source

Metabolic Syndrome and the Risk of Thyroid Cancer: A Nationwide Population-Based Cohort Study

Thyroid, 2020
Background: The association of metabolic syndrome and its components with the risk of thyroid cancer is unclear. Thus, we conducted a large-scale, nationwide, population-based, cohort study to investigate this relationship.
Joo-Hyun Park, Moonyoung Choi, Jung-Hun Kim, Jaemin Kim, Kyungdo Han, B. Kim, Do-Hoon Kim, Y. Park   +7 more
semanticscholar   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Childhood Thyroid Cancers

, 2021
[No abstract available]
Çelik A., Divarci E.
openaire   +2 more sources

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

Nature Communications, 2020
Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis at 22.4 million genetic markers in up to 119,715 individuals and identify 74
Wei Zhou, B. Brumpton, O. Kabil, J. Gudmundsson, G. Thorleifsson, Josh Weinstock, M. Zawistowski, J. Nielsen, L. Chaker, M. Medici, A. Teumer, S. Naitza, S. Sanna, U. Schultheiss, A. Cappola, J. Karjalainen, M. Kurki, M. Oneka, P. Taylor, L. Fritsche, S. Graham, B. Wolford, William Overton, Humaira Rasheed, E. Haug, M. Gabrielsen, A. Skogholt, I. Surakka, G. Davey Smith, Anita Pandit, Tanmoy Roychowdhury, W. Hornsby, J. Jónasson, L. Senter, S. Liyanarachchi, M. Ringel, Li Xu, L. Kiemeney, Huiling He, R. Netea-Maier, J. Mayordomo, T. Plantinga, J. Hrafnkelsson, H. Hjartarson, E. Sturgis, A. Palotie, M. Daly, Cintia E. Citterio, P. Arvan, C. Brummett, M. Boehnke, A. de la Chapelle, K. Stefánsson, K. Hveem, C. Willer, B. Åsvold   +55 more
semanticscholar   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Apatinib vs Placebo in Patients With Locally Advanced or Metastatic, Radioactive Iodine–Refractory Differentiated Thyroid Cancer [PDF]

, 2021
Yansong Lin, Shukui Qin, Zhiyong Li, Hui Yang, Wei Fu, Shaohua Li, Wenxin Chen, Zairong Gao, Weibing Miao, Huiqin Xu, Qing Zhang, Xinming Zhao, Jiandong Bao, Linfa Li, Ren Yuan, Chenghe Lin, Shanghua Jing, Qingjie Ma, Jun Liang, Guang Chen, Hong Zhang, Yifan Zhang, Xianfeng Zhou, Yaxiong Sang, Zhiguo Hou   +24 more
openalex   +1 more source

Updates on the Management of Thyroid Cancer

Hormone and Metabolic Research, 2020
The diagnostic modalities, stratification tools, and treatment options for patients with thyroid cancer have rapidly evolved since the development of the American Thyroid Association (ATA) guidelines in 2015.
Katherine Araque, Sriram Gubbi, J. Klubo-Gwiezdzinska   +2 more
semanticscholar   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Methionyl-tRNA synthetase 1 expression, the possibility as a diagnostic and prognostic factor in papillary thyroid cancer

BMC Cancer
Background Methionyl-tRNA synthetase 1 (MARS1) is a critical enzyme in translation initiation, responsible for catalyzing the transfer of Met to the initiator tRNA.
Seulkee Park, Jun Sung Lee, Ho Jung Jeong, Hyeok Jun Yun, Seok-Mo Kim, Ji Hae Nahm, Hojin Chang, Yong Sang Lee, Hang-Seok Chang   +8 more
doaj   +1 more source