Results 61 to 70 of about 5,157,057 (389)

Preoperative Ultrasonography Predicts Level II Lymph Node Metastasis in N1b Papillary Thyroid Carcinoma: Implications for Surgical Planning

Biomedicines
Purpose: To investigate whether preoperative ultrasonographic (US) features of the index cancer and metastatic lymph nodes (LNs) are associated with level II LN metastasis in N1b papillary rmfthyroid carcinoma (PTC) patients.
Na Lae Eun, Jeong-Ah Kim, Yangkyu Lee, Ji Hyun Youk, Hyeok Jun Yun, Hojin Chang, Seok-Mo Kim, Yong Sang Lee, Hang-Seok Chang, Hyejin Yang, Soyoung Jeon, Eun Ju Son   +11 more
doaj   +1 more source

SoLAT (Sorafenib Lenvatinib alternating treatment): a new treatment protocol with alternating Sorafenib and Lenvatinib for refractory thyroid Cancer

BMC Cancer, 2018
Background In the last decade, several tyrosine kinase inhibitors (TKIs), which disrupt pathways involved in the proliferation and tumorigenesis of thyroid cancer, have been extensively studied. Two different TKIs, lenvatinib and sorafenib, were recently
Soo Young Kim, Seok-Mo Kim, Ho-Jin Chang, Bup-Woo Kim, Yong Sang Lee, Cheong Soo Park, Ki Cheong Park, Hang-Seok Chang   +7 more
doaj   +1 more source

Survival With Lenvatinib for the Treatment of Progressive Anaplastic Thyroid Cancer: A Single-Center, Retrospective Analysis

Frontiers in Endocrinology, 2020
Background: Survival rates for anaplastic thyroid cancer (ATC) have not improved in the past four decades; however, preliminary clinical data indicate that lenvatinib may provide efficacy benefits for patients with ATC.
Soo Young Kim, Seok-Mo Kim, Jun Won Kim, Ik Jae Lee, Tae Joo Jeon, Hojin Chang, Bup-Woo Kim, Yong Sang Lee, Hang-Seok Chang, Cheong Soo Park   +9 more
doaj   +1 more source

A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid. Is conservative treatment always advised? [PDF]

, 2015
Introduction: Struma ovarii is an ovarian teratoma, represented in more than 50% by thyroid tissue. Five percent of struma ovarii cases have been proven to be malignant and, as in the thyroid gland, papillary thyroid carcinoma is the most common ...
Bianchi, Loredana, Brusca, Nunzia, Cannas, Pina, Centanni, Marco, Del Duca, Susanna Carlotta, D’Agostini, Antonio, Gargano, Lucilla, Salvatori, Rita, Santaguida, Maria Giulia, Virili, Camilla   +9 more
core   +2 more sources

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Role of Heterotypic Neutrophil-in-Tumor Structure in the Prognosis of Patients With Buccal Mucosa Squamous Cell Carcinoma

Frontiers in Oncology, 2020
ObjectiveTo analyze the role of frequency of heterotypic neutrophil-in-tumor structure (FNiT) in the prognosis of patients with buccal mucosa squamous cell carcinoma (BMSCC).MethodsIn vitro, we cocultured BMSCC cell line-H157 with neutrophils to form ...
Jie Fan, Jie Fan, Qigen Fang, Yang Yang, Meng Cui, Ming Zhao, Jinxing Qi, Ruihua Luo, Wei Du, Wei Du, Shanting Liu, Qiang Sun   +11 more
doaj   +1 more source

Concurrent papillary thyroid cancer and parathyroid adenoma as a rare condition: A case report [PDF]

, 2012
Although the pathological relationship between parathyroid and thyroid diseases is common, an association between parathyroid adenoma and thyroid cancer is rare.
Assadi, M., Farrokhi, S., Jallalat, S., Javadi, H., Mogharrabi, M., Moshtaghi, D., Nabipour, I., Riazi, A., Semnani, S.   +8 more
core   +1 more source

Thyroid cancer and nonsteroidal anti-inflammatory drug use: a pooled analysis of patients older than 40 years of age [PDF]

, 2015
Background: Cyclooxygenase (COX-2) has been associated with tumor growth and metastasis in several cancers, including thyroid cancer. For this reason, several investigators have studied COX-2 inhibitors in preclinical models of thyroid cancer and found ...
Kebebew, Electron, Kitahara, Cari M, Liao, Linda M, Linet, Martha, Nilubol, Naris, Park, Yikyung, Patel, Dhaval   +6 more
core   +2 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Comparison of the degree of patient satisfaction between transoral thyroidectomy and open thyroidectomy: a survey-based study

BMC Surgery
Background Recent advances in thyroid surgery techniques have increased the number of patients undergoing transoral thyroidectomy, and many patients are concerned about post-thyroidectomy cosmetic effects. This study aimed to compare patient satisfaction
Jun Sung Lee, Jooyoung Oh, Jayyoung Bae, Jin Seok Lee, Hyeok Jun Yun, Seok-Mo Kim, Hojin Chang, Yong Sang Lee, Young Song, Hang-Seok Chang   +9 more
doaj   +1 more source