Results 181 to 190 of about 1,994,828 (407)

Transoral Robotic Surgery (TORS) for Head and Neck Cancer in the Elderly Population: Functional Outcomes, Survival, and Complications

open access: yesHead &Neck, EarlyView.
ABSTRACT Objective To compare functional and oncologic outcomes in elderly (≥ 70 years) and nonelderly (< 70 years) patients after transoral robotic surgery (TORS). Methods A retrospective chart review was conducted on 114 patients who underwent TORS for head and neck squamous cell carcinoma between 2012 and 2022.
Erim Pamuk   +6 more
wiley   +1 more source

Nomogram for Predicting Osteoradionecrosis After Fibula Free Flap for Mandibular Reconstruction

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Osteoradionecrosis (ORN) is a severe complication following radiotherapy (RT), particularly after mandibular reconstruction with a fibula free flap. Risk prediction remains challenging due to limited data. Methods We conducted a multicenter retrospective study including 294 patients who underwent fibula free flap reconstruction and ...
Andrea Costantino   +15 more
wiley   +1 more source

No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]

open access: yes, 1933
G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Chrousos, G. P.   +3 more
core  

Recurrent Thyroid Carcinoma [PDF]

open access: yesEar, Nose & Throat Journal, 2008
Sofia, Avitia   +2 more
openaire   +2 more sources

Brain Metastases From Differentiated Thyroid Cancer in the Era of Targeted Therapies: A Multi‐Center Retrospective Cohort

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Brain metastases (BM) of differentiated thyroid carcinoma (DTC) are associated with unfavorable prognosis. This study evaluated BM management strategies and patients' outcomes. Methods A retrospective review of patients diagnosed with DTC and BM at Tel Aviv Sourasky and Rabin Medical Centers between 1985 and 2024. Clinical features,
Liyona Kampel   +9 more
wiley   +1 more source

Outcomes and risk factors of hemorrhage in patients with resected brain metastases

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Brain metastases may present with hemorrhage, yet risk factors and clinical outcomes remain unclear. Based on a cohort of 880 patients with resected brain metastases, this study identified tumor volume and primary tumor histology (melanoma and non‐small cell lung cancer) as key predictors of hemorrhage.
Melisa S. Guelen   +17 more
wiley   +1 more source

Integrated Genomic Characterization of Papillary Thyroid Carcinoma

open access: yesCell, 2014
N. Agrawal   +242 more
semanticscholar   +1 more source

Tumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis

open access: yesiLABMED, EarlyView.
We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang   +6 more
wiley   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

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