Results 181 to 190 of about 1,994,828 (407)
Nomogram for Predicting Osteoradionecrosis After Fibula Free Flap for Mandibular Reconstruction
Head &Neck, EarlyView.ABSTRACT Background
Osteoradionecrosis (ORN) is a severe complication following radiotherapy (RT), particularly after mandibular reconstruction with a fibula free flap. Risk prediction remains challenging due to limited data. Methods
We conducted a multicenter retrospective study including 294 patients who underwent fibula free flap reconstruction and ...Andrea Costantino, Bianca Festa, Filippo Marchi, Chung‐Kan Tsao, Raul Pellini, Luca Gazzini, Peter T. Dzięgielewski, Mario Ciniglio, Francesco Mazzola, Luca Calabrese, Antonio Sarno, Giampiero Parrinello, Linda Chow, Jyh‐Kwei Chen, Giorgio Peretti, Armando De Virgilio +15 morewiley +1 more sourceNo evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]
, 1933 G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...Chrousos, G. P., Karl, M., Reincke, Martin, Travis, W. +3 morecore Brain Metastases From Differentiated Thyroid Cancer in the Era of Targeted Therapies: A Multi‐Center Retrospective Cohort
Head &Neck, EarlyView.ABSTRACT Background
Brain metastases (BM) of differentiated thyroid carcinoma (DTC) are associated with unfavorable prognosis. This study evaluated BM management strategies and patients' outcomes. Methods
A retrospective review of patients diagnosed with DTC and BM at Tel Aviv Sourasky and Rabin Medical Centers between 1985 and 2024. Clinical features, Liyona Kampel, Shaun Edalati, Eyal Yosefof, Anton Warshavsky, Gilad Horowitz, Nidal Muhanna, Hagit Shoffel‐Havakuk, Eyal Robenshtok, Aron Popovtzer, Inbar Finkel +9 morewiley +1 more sourceOutcomes and risk factors of hemorrhage in patients with resected brain metastases
International Journal of Cancer, EarlyView.What's New?
Brain metastases may present with hemorrhage, yet risk factors and clinical outcomes remain unclear. Based on a cohort of 880 patients with resected brain metastases, this study identified tumor volume and primary tumor histology (melanoma and non‐small cell lung cancer) as key predictors of hemorrhage.Melisa S. Guelen, Kiarash Ferdowssian, Niklas Jung, Hava N. Celik, Andrea Dell'Orco, Semil Eminovic, Anton Früh, Majd Samman, Güliz Acker, Arend Koch, Helena Radbruch, Michael Scheel, Mike P. Wattjes, Julia Onken, Peter Vajkoczy, Nils Hecht, Jawed Nawabi, David Wasilewski +17 morewiley +1 more sourceIntegrated Genomic Characterization of Papillary Thyroid Carcinoma
Cell, 2014 N. Agrawal, Rehan Akbani, B. A. Aksoy, Adrian Ally, H. Arachchi, S. Asa, J. Auman, Miruna Balasundaram, S. Balu, S. Baylin, M. Behera, Brady Bernard, R. Beroukhim, J. Bishop, Aaron D. Black, T. Bodenheimer, L. Boice, Moiz Bootwalla, Jay Bowen, R. Bowlby, C. Bristow, Robin Brookens, Denise Brooks, Robert Bryant, Elizabeth Buda, Y. Butterfield, T. Carling, R. Carlsen, S. Carter, S. Carty, T. Chan, Amy Y. Chen, A. Cherniack, Dorothy Cheung, L. Chin, Juok Cho, Andy Chu, E. Chuah, K. Cibulskis, G. Ciriello, A. Clarke, G. Clayman, L. Cope, J. Copland, K. Covington, Ludmila V. Danilova, Tanja Davidsen, John A. Demchok, D. Dicara, Noreen Dhalla, R. Dhir, Sheliann S. Dookran, Gideon Dresdner, Jonathan V. Eldridge, G. Eley, A. El-Naggar, S. Eng, J. Fagin, T. Fennell, R. Ferris, Sheila A Fisher, S. Frazer, J. Frick, S. Gabriel, I. Ganly, Jianjiong Gao, L. Garraway, J. Gastier-Foster, G. Getz, Nils Gehlenborg, R. Ghossein, R. Gibbs, T. Giordano, Karen Gómez-Hernández, J. Grimsby, Benjamin E. Gross, R. Guin, Angela Hadjipanayis, H. Harper, D. Hayes, David I Heiman, J. Herman, K. Hoadley, Matan Hofree, R. Holt, A. Hoyle, F. Huang, Meijuan Huang, C. Hutter, T. Ideker, L. Iype, A. Jacobsen, S. Jefferys, Corbin D. Jones, Steven J. M. Jones, K. Kasaian, E. Kebebew, F. Khuri, Jaegil Kim, R. Kramer, R. Kreisberg, R. Kucherlapati, D. Kwiatkowski, M. Ladanyi, Phillip H. Lai, P. Laird, E. Lander, M. Lawrence, Darlene Lee, E. Lee, Semin Lee, William Lee, K. Leraas, T. Lichtenberg, Lee T Lichtenstein, Pei Lin, Shiyun Ling, Jinze Liu, Wenbin Liu, Yingchun Liu, V. Livolsi, Yiling Lu, Yussanne Ma, Harshad S. Mahadeshwar, M. Marra, Michael Mayo, D. McFadden, S. Meng, M. Meyerson, P. Mieczkowski, Michael B. Miller, G. Mills, Richard A. Moore, Lisle E. Mose, A. Mungall, Bradley A. Murray, Y. Nikiforov, M. Noble, A. Ojesina, T. Owonikoko, B. Ozenberger, A. Pantazi, Michael G Parfenov, P. Park, J. Parker, Evan O. Paull, C. Pedamallu, C. Perou, J. Prins, A. Protopopov, S. Ramalingam, N. Ramirez, Ricardo Ramirez, Benjamin J. Raphael, W. Rathmell, X. Ren, Sheila M. Reynolds, Esther Rheinbay, M. Ringel, M. Rivera, J. Roach, A. G. Robertson, Mara W Rosenberg, M. Rosenthal, S. Sadeghi, G. Saksena, C. Sander, Netty G Santoso, J. Schein, N. Schultz, S. Schumacher, R. Seethala, J. Seidman, Y. Şenbabaoğlu, S. Seth, S. Sharpe, K. Shaw, J. Shen, R. Shen, S. Sherman, Margi Sheth, Yan Shi, I. Shmulevich, G. Sica, J. Simons, Rileen Sinha, Payal Sipahimalani, R. Smallridge, H. Sofia, Matthew G. Soloway, Xingzhi Song, C. Sougnez, C. Stewart, P. Stojanov, Joshua M. Stuart, S. O. Sumer, Yichao Sun, B. Tabak, Angela Tam, Donghui Tan, Jiabin Tang, R. Tarnuzzer, B. Taylor, N. Thiessen, L. Thorne, V. Thorsson, R. Tuttle, C. Umbricht, D. V. Berg, Fabio Vandin, Umadevi Veluvolu, R. Verhaak, Michelle Vinco, Douglas Voet, Vonn Walter, Zhining Wang, S. Waring, P. Weinberger, Nils Weinhold, J. Weinstein, D. Weisenberger, D. Wheeler, M. Wilkerson, Jocelyn Wilson, M. Williams, D. Winer, L. Wise, Junyuan Wu, Liu Xi, A. W. Xu, Liming Yang, Lixing Yang, Travis Zack, M. Zeiger, Dong Zeng, J. Zenklusen, N. Zhao, Hailei Zhang, Jianhua Zhang, J. Zhang, Wei Zhang, E. Zmuda, L. Zou +242 moresemanticscholar +1 more sourceTumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis
iLABMED, EarlyView.We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.Ping Yang, Xueying Zhang, Wen Deng, Fangning Gao, Shujia Peng, Guoqiang Bao, Lijuan Yuan +6 morewiley +1 more sourceHypervision Proton Surgery: The Future Direction of Proton Therapy
iNew Medicine, EarlyView.ABSTRACT
Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...Li Li, Shuanghu Yuanwiley +1 more source