Results 301 to 310 of about 1,895,514 (380)

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

open access: yesBritish Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng   +3 more
wiley   +1 more source

Clonal Hematopoiesis and Solid Cancers

open access: yesCancer Science, EarlyView.
This review explores the relationship between clonal hematopoiesis and solid cancers. Clonal hematopoiesis mutations influence the tumor microenvironment by altering immune regulation, inflammation, and angiogenesis. Understanding these mutations has important clinical implications, including their role in prognosis, treatment response, and potential ...
Yen T. M. Nguyen   +3 more
wiley   +1 more source

Paediatric Thyroid Carcinoma: The Genetic Revolution and Its Implications for Therapy and Outcomes. [PDF]

open access: yesCancers (Basel)
Vanderniet JA   +6 more
europepmc   +1 more source

Hypoxia Inhibitor Improves Iodine Uptake Disorder in Thyroid Cancer Through the hsa_circ_0023990/miR‐448/DNMT1/NIS Axis

open access: yesCancer Science, EarlyView.
Our study reveals that hypoxia inhibitors ameliorate iodine uptake dysfunction in thyroid cancer by acting on the hsa_circ_0023990/miR‐448/DNMT1/NIS signaling pathway. ABSTRACT This research seeks to investigate how hypoxia inhibitors enhance iodine uptake in thyroid cancer cells. Clinical samples were gathered and assessed for hsa_circ_0023990, DNMT1,
Ruiqin Gou   +5 more
wiley   +1 more source

Molecular Landscape and Therapeutic Strategies in Pediatric Differentiated Thyroid Carcinoma.

open access: yesEndocr Rev
Yang AT   +11 more
europepmc   +1 more source

CARCINOMA OF THE THYROID GLAND

open access: yesAnnals of Surgery, 1950
Robert G. Chambers   +2 more
openaire   +4 more sources

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