Results 311 to 320 of about 1,895,514 (380)

ACSM5 Regulates Ferroptosis in Hepatocellular Carcinoma by Up‐Regulating POR and Modulating Lipid Metabolism

Cancer Science, EarlyView.
ACSM5 induced ferroptosis in HCC by up‐regulating cytochrome P450 oxidoreductase (POR). The metabolic transformation of linoleic acid to arachidonic acid was also promoted by ACSM5; thereby, the sensitivity to ferroptosis was elevated. ABSTRACT The medium‐chain fatty acyl‐CoA synthetase‐5 (ACSM5) plays a crucial role in the development of some cancers.
Zhengqiang Wu, Xiaofeng Xiong, Mingyi Dong, Linfei Luo, Zixiang Huang, Kedong Xu, Lianwu Zhao, Fenfen Wang, Zhili Wen   +8 more
wiley   +1 more source

Polarity Gene PARD6B Promotes Tumor Growth of Colorectal Cancer via Increasing MYC Expression

Cancer Science, EarlyView.
Partitioning Defective 6B (PARD6B), a polarity gene, functions as a scaffold node for the Par protein complex. In this study, we showed that highly expressed PARD6B could promote CRC growth by upregulating MYC expression while suppressing miR‐34c expression.
Kosuke Hirose, Takaaki Masuda, Hajime Otsu, Taro Tobo, Kiyotaka Hosoda, Tadashi Abe, Yusuke Nakano, Masahiro Hashimoto, Takanari Tatsumi, Tomohiko Ikehara, Takashi Ofuchi, Shinsaku Itoyama, Yuki Ando, Yasuo Tsuda, Yusuke Yonemura, Keishi Sugimachi, Eiji Oki, Tomoharu Yoshizumi, Koshi Mimori   +18 more
wiley   +1 more source

Single-Nucleotide Polymorphisms of BRCA1 and BRCA2 and Risk of Papillary Thyroid Carcinoma. [PDF]

Cancers (Basel)
Song CM, Kim YJ, Cheong HS, Ji YB, Tae K.   +4 more
europepmc   +1 more source

Epigenetically‐Upregulated CD98 Shed Light on the Precancerous Diagnosis and Prognosis Prediction of Esophageal Cancer

Cancer Science, EarlyView.
This study confirmed that hypomethylation‐induced upregulation of CD98 promoted ESCC cell proliferation by regulating the cell cycle and was correlated with poorer overall survival of ESCC patients. Combined panels of immunohistochemistry (CD98 and P53) are recommended for accurate diagnosis of esophageal precancerous lesions.
Xue Zhang, Mengfei Sun, Na Li, Jie Yu, Wenjie Wang, Ju Yang, Hongyan Wu, Linyue Zhao, Huakun Zhang, Lan Yang, Feng Li, Qi Sun, Yunzhao Chen, Xiaobin Cui   +13 more
wiley   +1 more source

Can mutation abundance assess the biological behavior of BRAF^V600E-positive papillary thyroid carcinoma? [PDF]

J Transl Med
Ni Y, Song P, Lin X, Shi J, Shi Q, Li Y, Zhu S, Zhou T, Xun Y, Zhang S, Ren X, Lu K, Wu F, Wang W, Zhao P, Zhou R, Zhang W, Li D, Zhang J, Chen C, Mao L, Zhou L, Pan G, Peng Y, Yu Y, Chen Y, Ni R, Luo G, Zhang Y, Fang J, Zheng H, Luo D.   +31 more
europepmc   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

Synchronous presentation of Hodgkin lymphoma and papillary thyroid carcinoma in a young patient: a case review. [PDF]

J Surg Case Rep
Aldeligan SH, AlQahtani AS, Aljunaydil A, Alzahrani N, Alakeel F, Althobaiti BT, Bokhari A.   +6 more
europepmc   +1 more source

Combining Procalcitonin and Calcitonin for the Diagnosis of Medullary Thyroid Cancer: A Two‐Step Approach

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Calcitonin (CT) represents the most important biochemical marker of medullary thyroid cancer (MTC), but has certain limits. Procalcitonin (ProCT) has been recognized as an alternative or additional marker for MTC. The aim of the study is to evaluate prospectively the role of ProCT combined with CT in the identification of MTC ...
Cristina Clausi, Simona Censi, Emma Zanin, Giulia Messina, Ilaria Piva, Daniela Basso, Isabella Merante Boschin, Loris Bertazza, Francesca Torresan, Maurizio Iacobone, Fiammetta Battheu, Susi Barollo, Jacopo Maria Arnone, Caterina Mian   +13 more
wiley   +1 more source

Papillary Thyroid Carcinoma Infiltrating a Parathyroid Adenoma: A Case Report. [PDF]

Cureus
McLuckie A, Thornton SB, Andree R, O'Neil S.   +3 more
europepmc   +1 more source