Results 131 to 140 of about 10,218,078 (407)

Thyroglobulin-to-tumor volume ratio combined with ultrasound features for diagnosing thyroid follicular neoplasms

Frontiers in Endocrinology
ObjectiveCurrent preoperative diagnostics inadequately differentiate benign from malignant thyroid follicular neoplasms. This study evaluated the diagnostic utility of thyroid function markers and contrast-enhanced ultrasound (CEUS) features in ...
Xixi Zhu, Xixi Zhu, Fen Liu, Jiaye Liu, Jiaye Liu, Zhihui Li, Yu Ma   +6 more
doaj   +1 more source

Role of the T and B lymphocytes in pathogenesis of autoimmune thyroid diseases [PDF]

, 2018
Marta Rydzewska, Michał Jaromin, Izabela Elżbieta Pasierowska, Karlina Stożek, Artur Bossowski   +4 more
openalex   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

The impacts of vitamin D supplementation on serum levels of thyroid autoantibodies in patients with autoimmune thyroid disease: a meta-analysis [PDF]

PeerJ
Background Although vitamin D (VitD) deficiency had been found with close relationship with autoimmune thyroid disorders (AITD), the findings about the impacts of VitD supplementation on the production of anti-thyroid peroxidase (TPOAb) and anti ...
Dongdong Luo, Bojuan Li, Zhongyan Shan, Weiping Teng, Qigui Liu, Jing Li   +5 more
doaj   +2 more sources

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Predicting dysthyroid optic neuropathy in moderate-to-severe thyroid eye disease: a clinically applicable nomogram

European Thyroid Journal
Objective: Dysthyroid optic neuropathy (DON) is a severe complication of thyroid eye disease (TED) with limited early detection methods. This study aimed to investigate the clinical characteristics of patients with TED who developed DON and to establish ...
Ruolin Hu, Siqi Tang, Xinyu Liu, Zewei Liu, Zhipeng Cui, Jingyue Chen, Yanan Wang, Feixue Jiang, Jingyi Zhu, Chao Wan, Yizhou Sun, Lei Shi, Zheng Wang, Chenyan Li, Xiaohui Yu, Chuyuan Wang, Weiwei Wang, Yaxin Lai, Yanli Cao, Xiaoli Wang, Yushu Li, Zhongyan Shan, Weiping Teng   +22 more
doaj   +1 more source

Discussion on the Diagnosis of Malignant Disease of the Thyroid Gland. [PDF]

, 1925
James Berry
openalex   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

Advanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao, Jiakang Shao, Quanzhi Li, Yizhou Tan, Liangliang Huang, Xiaorong Xu, Ji Qi, Julin Xiao, Wenwen Li, Zhong Wen, Le Wang, Xu Liu, Qing Yang, Ying Gu   +13 more
wiley   +1 more source

The development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men

Thyroid Research
Objective Vitamin D(VitD) deficiency has been found prevalent among patients with thyroid autoimmunity (TAI). This study aimed to investigate whether low VitD2 or VitD3 potentially contributed to the development of TAI in euthyroid male patients, which ...
Dongdong Luo, Chenxi Zhang, Bingrui Gao, Deping Wang, Zhaoying Chen, Kan Chen, Bojuan Li, Song Leng, Jing Li   +8 more
doaj   +1 more source

Autoimmune Thyroid Disease [PDF]

International Journal of Dermatology, 1981
Marked alterations in the level of circulating thyroid hormone frequently induce cutaneous changes. Such visible sequelae of hyperthyroidism or hypothyroidism can be among the first manilestationsot thyroid dysfunction. The etiology of such thyroid dysfunction is frequently attributable to autoimmune thyroid disease, as manifested by Graves' disease ...
openaire   +3 more sources