Results 221 to 230 of about 9,915,167 (360)

Thyroid disease and breast cancer, benign breast neoplasm: a two-sample Mendelian randomization study. [PDF]

BMC Womens Health
Wang B, Ling Y, Zhang H, Liu Y, Yuan J, Zhang Y, Yang M.   +6 more
europepmc   +1 more source

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi, Benedetta Massetto, Megan Fitzgerald, Kha Le, Stanley Wang, Ifong Kan‐Eng, Meenakshi Venkatraman, Naqvi Mohammad, Lawrence Blatt, Tse‐I Lin, Sushmita M. Chanda, John Fry   +11 more
wiley   +1 more source

Impact of telomere length on autoimmune thyroid disease in Europeans: insights from Mendelian randomization. [PDF]

Clinics (Sao Paulo)
Hu G, Yu Y, Yin Y, Yang X, Yu R, Xiang Q.   +5 more
europepmc   +1 more source

A Clinical Study on Surgically Managed Thyroid Diseases: Trend of Thyroid Operation in Catholic Medical Center, Korea from 1988 to 1992. [PDF]

, 1998
Kim Hk, Moon Sd, Chang Sa, Ahn Yb, Song Kh, JH Han, Yoo Sj, Lee Jm, Son Hs, Yoon Kh, Kang Mi, Cha By, Lee Kw, Son Hy, Sung-Koo Kang   +14 more
openalex  

Impact of Antihypertensive Treatment on Outcomes of Adjuvant Bevacizumab for Ovarian Cancer (IATRO), Results from a Nationwide Emulated Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Antiangiogenic therapy with bevacizumab improves outcomes in ovarian cancer but induces hypertension, leading to major adverse cardiovascular events (MACE). While calcium channel blockers (CCBs) and angiotensin‐converting enzyme inhibitors (ACEi) are recommended for managing bevacizumab‐associated hypertension, their impacts on cancer progression and ...
Floriane Jochum, Élise Dumas, Joe‐Elie Salem, Stéphane Ederhy, Anne‐Sophie Hamy, Lise Lecointre, Enora Laas, Fabien Reyal, Fabrice Lecuru, Cherif Akladios, Paul Gougis   +10 more
wiley   +1 more source

Resistance to Thyroid Hormone Beta and Coexisting Thyroid Disease: Diagnostic and Therapeutic Challenges Illustrated by Two Cases. [PDF]

Case Rep Endocrinol
Ribeiro S, Varela A, Queirós J.
europepmc   +1 more source

Maternal Thyroid Disease and Preterm Birth: Systematic Review and Meta-Analysis.

Journal of Clinical Endocrinology and Metabolism, 2015
P. Sheehan, A. Nankervis, E. Araújo Júnior, F. da Silva Costa   +3 more
semanticscholar   +1 more source

An Evaluation of the Drug Interaction Potential of Encorafenib in Combination With Binimetinib Using the Inje Cocktail in Patients With Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
A clinical drug–drug interaction (DDI) study was designed to evaluate the effect of single and multiple oral doses of encorafenib on the single oral dose pharmacokinetics (PK) of the cytochrome P450 (CYP) enzyme probe substrates, losartan (CYP2C9), midazolam (CYP3A4), caffeine (CYP1A2), omeprazole (CYP2C19), and dextromethorphan (CYP2D6) administered ...
Joseph Piscitelli, Micaela B. Reddy, Lance Wollenberg, Laurence Del Frari, Jason Gong, Kyle Matschke, Jason H. Williams   +6 more
wiley   +1 more source

Autoimmune Thyroid Disease in the United States: Population Prevalence, Diagnosis Rates, and Trends. [PDF]

J Endocr Soc
Dillon CF, Weisman MH, Leung AM, Brent GA, Miller FW.   +4 more
europepmc   +1 more source

Ultrasound elastography in thyroid disease.

Medical ultrasonography, 2015
S. Dudea, C. Botar-Jid
semanticscholar   +1 more source