Results 281 to 290 of about 9,788,907 (408)

Modulation of class-II antigen expression in human thyroid epithelial cell cultures [PDF]

open access: yes, 1987
Arnholdt, H.   +4 more
core   +1 more source

First‐in‐Human Phase 1 Study to Evaluate the Clinical Pharmacology Properties of RBN‐3143, a Novel Inhibitor of Mono‐Adenosine Diphosphate Ribosyltransferase‐PARP14

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract RBN‐3143 is an inhibitor of PARP14 in development for inflammatory diseases. Multiple assessments were conducted to evaluate the clinical pharmacology properties of RBN‐3134. A randomized, double‐blind, placebo‐controlled study assigned healthy volunteers (HVs) to single ascending doses (SADs) (25‐1000 mg) or multiple ascending doses (MADs ...
Thomas M. Polasek   +9 more
wiley   +1 more source

Primary Hodgkinʼs Disease of the Thyroid

open access: green, 1963
T. W. Roberts, Rudolph G. Howard
openalex   +2 more sources

Exploring the Association Between Intra‐Patient Variability in Trough Concentration of Pazopanib and Clinical Outcomes in Renal Cell Carcinoma and Soft Tissue Sarcoma Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pazopanib is an oral tyrosine kinase inhibitor used in patients with either metastatic renal cell carcinoma or soft tissue sarcoma. Pazopanib has a high interindividual variability in pharmacokinetics and pharmacodynamics and a well‐established exposure–response relationship. Therefore, therapeutic drug monitoring is recommended to improve the efficacy–
Amy Rieborn   +6 more
wiley   +1 more source

Should we routinely assess ovarian reserve in girls and young women with autoimmune thyroid disease? [PDF]

open access: yesHeliyon
Wędrychowicz A   +5 more
europepmc   +1 more source

A Genetic Twist: Cytologic Evaluation of Pancreatic Adenocarcinoma and Steatohepatitic Hepatocellular Carcinoma in a Patient With a Rare POLE Mutation

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Mutations in the DNA polymerase epsilon (POLE) gene are associated with an increased risk of various malignancies, including colorectal and other gastrointestinal, endometrial, ovarian, breast, and brain cancers. In extremely rare cases, POLE mutations have also been associated with pancreatic and hepatobiliary carcinomas.
Lynn Messersmith   +3 more
wiley   +1 more source

Hyperthyroid heart disease: Diagnostic and therapeutic aspects [PDF]

open access: yes, 1990
Reinwein, Dankwart   +2 more
core   +1 more source

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